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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
33.94
Human Site:
S476
Identified Species:
53.33
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
S476
A
Q
K
D
G
E
K
S
R
V
K
V
K
V
R
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
S709
A
Q
K
D
G
E
K
S
R
V
K
V
K
V
R
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
S476
P
Q
S
D
G
S
S
S
K
V
K
V
K
V
R
Dog
Lupus familis
XP_534515
1048
117305
S665
A
Q
K
D
G
E
K
S
R
V
K
V
K
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
S476
A
Q
K
D
G
E
K
S
R
V
K
V
K
V
R
Rat
Rattus norvegicus
Q66HA8
858
96400
S476
A
Q
K
D
G
E
K
S
K
V
K
V
K
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
S476
A
Q
K
D
G
E
K
S
K
V
K
V
K
V
R
Chicken
Gallus gallus
NP_001153170
856
96066
S476
A
Q
K
D
G
E
K
S
K
V
K
V
K
V
R
Frog
Xenopus laevis
P02827
647
70897
V347
G
S
T
R
I
P
K
V
Q
K
L
L
Q
D
F
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
S476
P
Q
A
S
G
E
S
S
K
V
K
V
K
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
I341
L
V
G
G
S
T
R
I
P
K
V
Q
S
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
G476
A
R
P
G
A
D
G
G
N
Q
K
V
K
V
K
Sea Urchin
Strong. purpuratus
Q06068
889
98600
I476
T
E
G
E
S
S
K
I
K
V
K
V
R
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
F392
P
T
L
R
V
R
P
F
K
F
E
D
I
H
P
Red Bread Mold
Neurospora crassa
O74225
707
78655
D407
I
E
F
T
W
E
K
D
A
D
I
P
D
E
D
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
66.6
100
N.A.
100
93.3
N.A.
93.3
93.3
6.6
66.6
N.A.
0
N.A.
33.3
33.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
100
100
26.6
73.3
N.A.
13.3
N.A.
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
7
0
7
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
54
0
7
0
7
0
7
0
7
7
7
14
% D
% Glu:
0
14
0
7
0
60
0
0
0
0
7
0
0
7
0
% E
% Phe:
0
0
7
0
0
0
0
7
0
7
0
0
0
0
7
% F
% Gly:
7
0
14
14
60
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
0
7
0
0
14
0
0
7
0
7
0
0
% I
% Lys:
0
0
47
0
0
0
67
0
47
14
74
0
67
0
7
% K
% Leu:
7
0
7
0
0
0
0
0
0
0
7
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
20
0
7
0
0
7
7
0
7
0
0
7
0
0
7
% P
% Gln:
0
60
0
0
0
0
0
0
7
7
0
7
7
0
0
% Q
% Arg:
0
7
0
14
0
7
7
0
27
0
0
0
7
0
60
% R
% Ser:
0
7
7
7
14
14
14
60
0
0
0
0
7
0
0
% S
% Thr:
7
7
7
7
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
7
0
0
7
0
67
7
74
0
74
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _