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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
23.33
Human Site:
S410
Identified Species:
36.67
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
S410
S
L
I
W
N
H
D
S
E
D
T
E
G
V
H
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
S643
S
L
I
W
N
H
D
S
E
D
T
E
G
V
H
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
A410
S
L
R
W
N
S
P
A
E
E
G
S
S
D
C
Dog
Lupus familis
XP_534515
1048
117305
S599
S
L
V
W
N
H
D
S
E
D
T
E
G
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
S410
S
L
V
W
N
H
D
S
E
E
T
E
G
V
H
Rat
Rattus norvegicus
Q66HA8
858
96400
S410
S
L
V
W
N
H
D
S
E
E
T
E
G
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
S410
S
L
V
W
S
N
D
S
E
D
T
D
G
A
H
Chicken
Gallus gallus
NP_001153170
856
96066
A410
S
L
L
W
N
T
E
A
E
D
T
E
G
V
H
Frog
Xenopus laevis
P02827
647
70897
A281
T
L
S
S
S
S
Q
A
S
I
E
I
D
S
L
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
A410
S
L
K
W
N
S
A
A
E
D
G
V
S
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
S275
A
K
R
T
L
S
S
S
T
E
A
T
I
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
N410
Y
R
I
R
L
S
W
N
S
T
G
E
N
G
G
Sea Urchin
Strong. purpuratus
Q06068
889
98600
E410
E
L
E
W
K
G
T
E
G
E
D
G
S
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
A326
E
P
V
T
K
A
L
A
Q
A
K
L
S
A
E
Red Bread Mold
Neurospora crassa
O74225
707
78655
G341
D
I
I
E
V
V
G
G
G
S
R
V
P
S
V
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
33.3
93.3
N.A.
86.6
86.6
N.A.
66.6
73.3
6.6
40
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
93.3
93.3
26.6
46.6
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
7
34
0
7
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% C
% Asp:
7
0
0
0
0
0
40
0
0
40
7
7
7
14
0
% D
% Glu:
14
0
7
7
0
0
7
7
60
34
7
47
0
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
7
7
14
0
20
7
47
7
7
% G
% His:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
47
% H
% Ile:
0
7
27
0
0
0
0
0
0
7
0
7
7
0
7
% I
% Lys:
0
7
7
0
14
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
74
7
0
14
0
7
0
0
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
54
7
0
7
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
0
0
0
7
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
0
7
14
7
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
60
0
7
7
14
34
7
47
14
7
0
7
27
14
0
% S
% Thr:
7
0
0
14
0
7
7
0
7
7
47
7
0
0
0
% T
% Val:
0
0
34
0
7
7
0
0
0
0
0
14
0
40
7
% V
% Trp:
0
0
0
67
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _