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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM131
All Species:
23.03
Human Site:
S275
Identified Species:
50.67
UniProt:
Q92545
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92545
NP_056163.1
1834
200810
S275
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Chimpanzee
Pan troglodytes
XP_515638
1883
205095
S324
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531794
1765
193338
V258
P
Q
N
D
A
I
T
V
H
F
K
P
I
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O70472
1829
200481
S274
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Rat
Rattus norvegicus
XP_237056
1873
204160
S321
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514076
1953
212261
S279
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Chicken
Gallus gallus
XP_001233589
1923
210583
S354
T
T
A
P
G
I
Y
S
S
T
E
M
L
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923340
1799
197701
S262
V
M
R
A
S
F
S
S
R
D
A
D
N
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7H4
1567
173302
D62
R
L
V
P
S
R
L
D
F
G
T
W
S
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498059
1831
205776
L276
S
K
L
A
E
E
P
L
Q
Y
W
D
I
R
P
Sea Urchin
Strong. purpuratus
XP_795113
1144
126924
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
N.A.
91.8
N.A.
89.6
87.8
N.A.
69.6
76.1
N.A.
61.1
N.A.
24.3
N.A.
24.9
23.1
Protein Similarity:
100
97.1
N.A.
93.8
N.A.
94.2
92.4
N.A.
78.5
84
N.A.
74.5
N.A.
41.3
N.A.
43.8
35.7
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
N.A.
20
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
6.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
55
19
10
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
10
0
19
0
55
0
% D
% Glu:
0
0
0
0
10
10
0
0
0
0
55
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
55
% F
% Gly:
0
0
0
0
55
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
64
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
10
10
0
0
0
0
55
0
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
55
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
64
0
0
10
0
0
0
0
10
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
10
0
0
10
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
19
0
10
64
55
0
0
0
10
0
0
% S
% Thr:
55
55
0
0
0
0
10
0
0
55
10
0
0
10
10
% T
% Val:
10
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
55
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _