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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGB
All Species:
6.97
Human Site:
Y423
Identified Species:
11.79
UniProt:
Q92521
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92521
NP_004846.4
554
65056
Y423
S
H
I
Q
K
V
C
Y
N
N
P
N
K
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852466
348
40905
Y228
T
H
I
Q
E
L
C
Y
N
N
R
N
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJQ0
542
63101
P412
N
H
I
Q
K
V
C
P
R
G
P
D
P
A
S
Rat
Rattus norvegicus
NP_001101636
542
63187
P412
S
H
I
Q
K
V
C
P
R
G
P
D
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514392
611
69924
S426
A
H
V
R
G
L
C
S
A
D
A
P
G
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7R2
531
61428
K411
S
G
I
Q
K
L
C
K
M
E
N
S
S
A
S
Zebra Danio
Brachydanio rerio
Q7SXZ1
536
62222
V405
H
V
L
Q
P
L
C
V
S
S
Q
S
P
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZM5
561
64988
K412
T
C
E
P
N
L
E
K
K
E
Q
Y
K
D
E
Honey Bee
Apis mellifera
XP_001122380
446
53291
N326
L
H
K
E
I
V
N
N
K
D
T
N
N
I
L
Nematode Worm
Caenorhab. elegans
Q23361
492
57131
L372
N
Y
P
G
F
D
A
L
N
Y
L
Q
F
Q
N
Sea Urchin
Strong. purpuratus
XP_788180
518
59872
S398
M
F
L
M
P
C
H
S
T
P
F
Y
S
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131169
550
62718
E421
L
F
H
Q
R
G
T
E
D
V
M
Y
Y
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568305
548
62683
P403
F
L
L
A
T
N
I
P
M
A
L
Y
M
S
L
Baker's Yeast
Sacchar. cerevisiae
P30777
616
72547
F458
G
S
I
E
V
M
K
F
L
H
E
E
P
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
56.1
N.A.
77.4
78.1
N.A.
52.8
N.A.
63.5
52.8
N.A.
38.3
33
21.8
43.6
Protein Similarity:
100
N.A.
N.A.
60.2
N.A.
85.7
85.3
N.A.
64.6
N.A.
77.4
72.1
N.A.
56.3
50.1
40.6
60.8
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
53.3
53.3
N.A.
20
N.A.
40
13.3
N.A.
6.6
20
6.6
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
73.3
66.6
N.A.
53.3
N.A.
60
53.3
N.A.
20
33.3
26.6
6.6
Percent
Protein Identity:
N.A.
38.9
N.A.
39.3
25.3
N.A.
Protein Similarity:
N.A.
58.4
N.A.
58.3
44.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
8
8
8
0
0
22
0
% A
% Cys:
0
8
0
0
0
8
50
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
15
0
15
0
8
0
% D
% Glu:
0
0
8
15
8
0
8
8
0
15
8
8
0
8
8
% E
% Phe:
8
15
0
0
8
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
8
8
0
8
8
8
0
0
0
15
0
0
8
0
0
% G
% His:
8
43
8
0
0
0
8
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
43
0
8
0
8
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
8
0
29
0
8
15
15
0
0
0
22
0
0
% K
% Leu:
15
8
22
0
0
36
0
8
8
0
15
0
0
8
15
% L
% Met:
8
0
0
8
0
8
0
0
15
0
8
0
8
0
0
% M
% Asn:
15
0
0
0
8
8
8
8
22
15
8
22
8
8
8
% N
% Pro:
0
0
8
8
15
0
0
22
0
8
22
8
29
8
15
% P
% Gln:
0
0
0
50
0
0
0
0
0
0
15
8
0
8
0
% Q
% Arg:
0
0
0
8
8
0
0
0
15
0
8
0
0
0
0
% R
% Ser:
22
8
0
0
0
0
0
15
8
8
0
15
15
22
43
% S
% Thr:
15
0
0
0
8
0
8
0
8
0
8
0
0
0
0
% T
% Val:
0
8
8
0
8
29
0
8
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
15
0
8
0
29
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _