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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGB All Species: 1.82
Human Site: S49 Identified Species: 3.08
UniProt: Q92521 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92521 NP_004846.4 554 65056 S49 Y F N T Q E K S A R R R G D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852466 348 40905
Cat Felis silvestris
Mouse Mus musculus Q9JJQ0 542 63101 T50 R G L L G E N T Y L V L F T I
Rat Rattus norvegicus NP_001101636 542 63187 N49 R R D L L G E N T Y L V L F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514392 611 69924 E53 K P C G K E V E I W A L G E I
Chicken Gallus gallus
Frog Xenopus laevis Q4V7R2 531 61428 T49 A G L F G E N T Y L V L A A V
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 I49 G I N I T V F I V L V R L L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZM5 561 64988 W51 Y G Y L T W E W V Q G I R S Y
Honey Bee Apis mellifera XP_001122380 446 53291
Nematode Worm Caenorhab. elegans Q23361 492 57131 P20 I I H I I L A P G T K V E E S
Sea Urchin Strong. purpuratus XP_788180 518 59872 L46 G L L I L L V L F R W M N V G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131169 550 62718 L49 R K V L V F A L A F R A A N A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_568305 548 62683 R49 F L F C L A F R V V N A L L I
Baker's Yeast Sacchar. cerevisiae P30777 616 72547 L58 K A F K Y G E L T W E W K F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 56.1 N.A. 77.4 78.1 N.A. 52.8 N.A. 63.5 52.8 N.A. 38.3 33 21.8 43.6
Protein Similarity: 100 N.A. N.A. 60.2 N.A. 85.7 85.3 N.A. 64.6 N.A. 77.4 72.1 N.A. 56.3 50.1 40.6 60.8
P-Site Identity: 100 N.A. N.A. 0 N.A. 6.6 0 N.A. 13.3 N.A. 6.6 13.3 N.A. 6.6 0 0 6.6
P-Site Similarity: 100 N.A. N.A. 0 N.A. 20 20 N.A. 33.3 N.A. 20 13.3 N.A. 20 0 20 6.6
Percent
Protein Identity: N.A. 38.9 N.A. 39.3 25.3 N.A.
Protein Similarity: N.A. 58.4 N.A. 58.3 44.4 N.A.
P-Site Identity: N.A. 13.3 N.A. 0 0 N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 15 0 15 0 8 15 15 8 8 % A
% Cys: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 29 22 8 0 0 8 0 8 15 0 % E
% Phe: 8 8 15 8 0 8 15 0 8 8 0 0 8 15 0 % F
% Gly: 15 22 0 8 15 15 0 0 8 0 8 0 15 0 15 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 15 0 22 8 0 0 8 8 0 0 8 0 0 22 % I
% Lys: 15 8 0 8 8 0 8 0 0 0 8 0 8 0 0 % K
% Leu: 0 15 22 29 22 15 0 22 0 22 8 22 22 15 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 15 0 0 0 15 8 0 0 8 0 8 8 8 % N
% Pro: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 22 8 0 0 0 0 0 8 0 15 15 15 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 8 15 0 0 15 15 8 0 0 0 8 8 % T
% Val: 0 0 8 0 8 8 15 0 22 8 22 15 0 8 8 % V
% Trp: 0 0 0 0 0 8 0 8 0 15 8 8 0 0 0 % W
% Tyr: 15 0 8 0 8 0 0 0 15 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _