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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
40.3
Human Site:
Y525
Identified Species:
63.33
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
Y525
D
C
D
N
L
E
Q
Y
F
I
Q
Q
G
G
G
Chimpanzee
Pan troglodytes
XP_515309
740
82400
Y525
D
C
D
N
L
E
Q
Y
F
I
Q
Q
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
Y525
D
C
D
N
L
E
Q
Y
F
M
Q
Q
G
G
G
Dog
Lupus familis
XP_848865
740
82396
Y525
D
C
D
N
L
E
Q
Y
F
M
Q
Q
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
Y525
D
C
D
N
L
E
Q
Y
F
M
Q
Q
G
G
G
Rat
Rattus norvegicus
Q641Y8
740
82479
Y525
D
C
D
N
L
E
Q
Y
F
M
Q
Q
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
Y525
D
C
D
N
M
E
Q
Y
F
I
Q
Q
G
G
G
Frog
Xenopus laevis
A2VD92
740
82328
Y525
D
C
D
N
M
E
Q
Y
F
I
Q
Q
G
G
G
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
Y525
D
C
D
N
M
E
Q
Y
F
I
K
Q
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
F524
D
C
D
N
L
E
R
F
L
R
Q
R
G
G
K
Honey Bee
Apis mellifera
XP_392325
733
81819
Y526
D
C
D
N
L
E
R
Y
L
K
Q
S
G
G
S
Nematode Worm
Caenorhab. elegans
P27639
402
45389
T211
Q
V
V
L
L
S
A
T
M
P
S
E
V
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
G442
E
N
W
L
C
I
N
G
F
P
A
T
S
I
H
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
A355
L
N
K
Y
L
E
T
A
S
Q
D
N
E
Y
K
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
K423
A
N
S
R
I
E
Q
K
V
E
V
V
D
P
R
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
86.6
N.A.
60
66.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
80
73.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% A
% Cys:
0
74
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
74
0
74
0
0
0
0
0
0
0
7
0
7
0
7
% D
% Glu:
7
0
0
0
0
87
0
0
0
7
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
67
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
74
74
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
7
7
0
0
0
34
0
0
0
7
0
% I
% Lys:
0
0
7
0
0
0
0
7
0
7
7
0
0
0
14
% K
% Leu:
7
0
0
14
67
0
0
0
14
0
0
0
0
7
0
% L
% Met:
0
0
0
0
20
0
0
0
7
27
0
0
0
0
0
% M
% Asn:
0
20
0
74
0
0
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
67
0
0
7
67
60
0
0
0
% Q
% Arg:
0
0
0
7
0
0
14
0
0
7
0
7
0
0
7
% R
% Ser:
0
0
7
0
0
7
0
0
7
0
7
7
7
0
7
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
0
% T
% Val:
0
7
7
0
0
0
0
0
7
0
7
7
7
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
67
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _