KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
35.45
Human Site:
Y496
Identified Species:
55.71
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
Y496
I
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Chimpanzee
Pan troglodytes
XP_515309
740
82400
Y496
V
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
Y496
I
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Dog
Lupus familis
XP_848865
740
82396
Y496
I
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
Y496
I
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Rat
Rattus norvegicus
Q641Y8
740
82479
Y496
I
K
I
L
K
G
E
Y
A
V
R
A
I
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
Y496
I
K
I
L
K
G
E
Y
T
V
R
A
I
K
E
Frog
Xenopus laevis
A2VD92
740
82328
Y496
I
K
V
L
K
G
E
Y
I
V
R
A
I
K
E
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
Y496
I
K
I
L
K
G
E
Y
T
V
R
A
I
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
C496
K
L
L
K
G
E
Y
C
V
H
A
I
D
K
H
Honey Bee
Apis mellifera
XP_392325
733
81819
C498
K
I
L
K
G
E
Y
C
I
R
A
I
K
E
H
Nematode Worm
Caenorhab. elegans
P27639
402
45389
R186
E
A
D
E
M
L
S
R
G
F
K
D
Q
I
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
K417
R
E
N
G
I
Q
G
K
Q
A
L
T
L
V
F
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
H330
S
L
E
L
S
A
S
H
N
I
T
Q
I
V
E
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
H398
P
A
Q
V
T
I
G
H
R
T
R
A
G
G
D
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
93.3
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
13.3
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
0
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
7
0
0
40
7
14
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
7
7
0
7
% D
% Glu:
7
7
7
7
0
14
60
0
0
0
0
0
0
7
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% F
% Gly:
0
0
0
7
14
60
14
0
7
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
14
0
7
0
0
0
0
14
% H
% Ile:
54
7
54
0
7
7
0
0
14
7
0
14
67
7
0
% I
% Lys:
14
60
0
14
60
0
0
7
0
0
7
0
7
67
0
% K
% Leu:
0
14
14
67
0
7
0
0
0
0
7
0
7
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
0
7
0
0
7
7
0
0
% Q
% Arg:
7
0
0
0
0
0
0
7
7
7
67
0
0
0
0
% R
% Ser:
7
0
0
0
7
0
14
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
14
7
7
7
0
0
0
% T
% Val:
7
0
7
7
0
0
0
0
7
60
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
60
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _