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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
35.15
Human Site:
Y135
Identified Species:
55.24
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
Y135
L
M
K
G
K
H
Y
Y
E
V
S
C
H
D
Q
Chimpanzee
Pan troglodytes
XP_515309
740
82400
Y135
L
M
K
G
K
H
Y
Y
E
V
S
C
H
D
Q
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
Y135
L
M
K
G
K
H
Y
Y
E
V
S
C
H
D
Q
Dog
Lupus familis
XP_848865
740
82396
Y135
L
T
K
G
K
H
Y
Y
E
V
S
C
H
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
Y135
L
L
K
G
K
H
Y
Y
E
V
S
C
H
D
Q
Rat
Rattus norvegicus
Q641Y8
740
82479
Y135
L
L
R
G
K
H
Y
Y
E
V
S
C
H
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
Y135
V
T
K
G
K
Y
Y
Y
E
V
S
C
H
D
Q
Frog
Xenopus laevis
A2VD92
740
82328
Y135
V
N
K
G
K
Y
Y
Y
E
V
S
C
H
D
Q
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
Y135
V
T
K
G
R
Y
Y
Y
E
V
A
C
H
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
F134
R
G
K
G
K
F
Y
F
E
A
T
V
T
D
E
Honey Bee
Apis mellifera
XP_392325
733
81819
F135
Q
G
K
D
K
Y
F
F
E
A
I
V
T
D
E
Nematode Worm
Caenorhab. elegans
P27639
402
45389
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
W101
G
G
R
G
G
G
G
W
N
N
R
S
G
G
W
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
N14
D
Q
Q
Y
N
K
T
N
Y
K
S
R
G
G
D
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
A81
D
V
S
M
P
D
A
A
A
E
P
V
A
D
K
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
80
80
66.6
N.A.
40
26.6
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
60
53.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
7
7
14
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% C
% Asp:
14
0
0
7
0
7
0
0
0
0
0
0
0
80
7
% D
% Glu:
0
0
0
0
0
0
0
0
74
7
0
0
0
0
14
% E
% Phe:
0
0
0
0
0
7
7
14
0
0
0
0
0
0
0
% F
% Gly:
7
20
0
74
7
7
7
0
0
0
0
0
14
14
0
% G
% His:
0
0
0
0
0
40
0
0
0
0
0
0
60
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
67
0
67
7
0
0
0
7
0
0
0
0
7
% K
% Leu:
40
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
20
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
7
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
60
% Q
% Arg:
7
0
14
0
7
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
60
7
0
0
0
% S
% Thr:
0
20
0
0
0
0
7
0
0
0
7
0
14
0
0
% T
% Val:
20
7
0
0
0
0
0
0
0
60
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
27
67
60
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _