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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX1 All Species: 37.58
Human Site: S725 Identified Species: 59.05
UniProt: Q92499 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92499 NP_004930.1 740 82432 S725 L E K E A Q T S F L H L G Y L
Chimpanzee Pan troglodytes XP_515309 740 82400 S725 L E K E A Q T S F L H L G Y L
Rhesus Macaque Macaca mulatta XP_001090643 740 82473 S725 L E K E A Q T S F L H L G Y L
Dog Lupus familis XP_848865 740 82396 S725 L E K E A Q T S F L H L G Y L
Cat Felis silvestris
Mouse Mus musculus Q91VR5 740 82482 S725 L E K E A Q T S F L H L G Y L
Rat Rattus norvegicus Q641Y8 740 82479 S725 L E K E A Q T S F L H L G Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90WU3 740 82466 S725 L E K E A Q T S F L H L G Y L
Frog Xenopus laevis A2VD92 740 82328 S725 L E K E A Q T S F L H L G Y L
Zebra Danio Brachydanio rerio XP_684782 740 82395 S725 L E R E A Q T S F L H L G Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNV3 727 80851 L713 T V R K L T E L E L Q S Q S L
Honey Bee Apis mellifera XP_392325 733 81819 A719 L S S L E S K A Q I W Y L K R
Nematode Worm Caenorhab. elegans P27639 402 45389 T388 K E I E S Y Y T T Q I E E M P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84W89 633 67608 A619 Y G G G Y G G A S S G G Y G G
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 R532 R G G Y G G N R Q R D G G W G
Red Bread Mold Neurospora crassa Q7S5R1 614 67729 K600 D A Y G S F Y K D I D P N K K
Conservation
Percent
Protein Identity: 100 99.8 99.5 97.6 N.A. 97.5 97.6 N.A. N.A. 93.2 89.7 84.8 N.A. 59.7 62.9 22.4 N.A.
Protein Similarity: 100 100 100 99.1 N.A. 99.4 99.5 N.A. N.A. 97 96 93.7 N.A. 76 78.7 36.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 13.3 6.6 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 26.6 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 23.9 23.6
Protein Similarity: N.A. N.A. N.A. 37.1 38.9 40.4
P-Site Identity: N.A. N.A. N.A. 0 6.6 0
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 60 0 0 14 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 7 0 14 0 0 0 0 % D
% Glu: 0 67 0 67 7 0 7 0 7 0 0 7 7 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 60 0 0 0 0 0 0 % F
% Gly: 0 14 14 14 7 14 7 0 0 0 7 14 67 7 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 14 7 0 0 0 0 % I
% Lys: 7 0 54 7 0 0 7 7 0 0 0 0 0 14 7 % K
% Leu: 67 0 0 7 7 0 0 7 0 67 0 60 7 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % P
% Gln: 0 0 0 0 0 60 0 0 14 7 7 0 7 0 0 % Q
% Arg: 7 0 14 0 0 0 0 7 0 7 0 0 0 0 7 % R
% Ser: 0 7 7 0 14 7 0 60 7 7 0 7 0 7 0 % S
% Thr: 7 0 0 0 0 7 60 7 7 0 0 0 0 0 0 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % W
% Tyr: 7 0 7 7 7 7 14 0 0 0 0 7 7 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _