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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX1 All Species: 10.3
Human Site: S700 Identified Species: 16.19
UniProt: Q92499 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92499 NP_004930.1 740 82432 S700 K R A A G G G S Y K G H V D I
Chimpanzee Pan troglodytes XP_515309 740 82400 S700 K R A A G G G S Y K G H V D I
Rhesus Macaque Macaca mulatta XP_001090643 740 82473 S700 K R A A G G G S Y K G H V D I
Dog Lupus familis XP_848865 740 82396 N700 K R A I G G G N Y K G H V D I
Cat Felis silvestris
Mouse Mus musculus Q91VR5 740 82482 N700 K R A A G G G N Y K G H V D V
Rat Rattus norvegicus Q641Y8 740 82479 N700 K R A A G G G N Y K G H V D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90WU3 740 82466 L700 K R A L G G G L Y K G H V D I
Frog Xenopus laevis A2VD92 740 82328 L700 R R A T G G G L Y K G H V D I
Zebra Danio Brachydanio rerio XP_684782 740 82395 L700 R R A T G G G L Y K G H V D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNV3 727 80851 K688 G K V V Y G Q K N L R T G S G
Honey Bee Apis mellifera XP_392325 733 81819 M694 Y G E K R A A M G S N Y Q N H
Nematode Worm Caenorhab. elegans P27639 402 45389 G363 I G R S G R F G R K G V A I N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84W89 633 67608 Y594 Y G G G G G G Y G G G G G Y G
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 G507 G G H P R Y G G G R G G R G G
Red Bread Mold Neurospora crassa Q7S5R1 614 67729 P575 I L R A A K Q P V P E E L L K
Conservation
Percent
Protein Identity: 100 99.8 99.5 97.6 N.A. 97.5 97.6 N.A. N.A. 93.2 89.7 84.8 N.A. 59.7 62.9 22.4 N.A.
Protein Similarity: 100 100 100 99.1 N.A. 99.4 99.5 N.A. N.A. 97 96 93.7 N.A. 76 78.7 36.2 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 93.3 N.A. N.A. 86.6 80 80 N.A. 6.6 0 20 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 86.6 86.6 86.6 N.A. 13.3 13.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 23.9 23.6
Protein Similarity: N.A. N.A. N.A. 37.1 38.9 40.4
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 40 7 7 7 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 7 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 14 27 7 7 74 74 74 14 20 7 80 14 14 7 20 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 60 0 0 7 % H
% Ile: 14 0 0 7 0 0 0 0 0 0 0 0 0 7 54 % I
% Lys: 47 7 0 7 0 7 0 7 0 67 0 0 0 0 7 % K
% Leu: 0 7 0 7 0 0 0 20 0 7 0 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 20 7 0 7 0 0 7 7 % N
% Pro: 0 0 0 7 0 0 0 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 14 0 0 0 0 0 7 0 0 % Q
% Arg: 14 60 14 0 14 7 0 0 7 7 7 0 7 0 0 % R
% Ser: 0 0 0 7 0 0 0 20 0 7 0 0 0 7 0 % S
% Thr: 0 0 0 14 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 0 0 7 7 0 0 0 0 7 0 0 7 60 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 0 0 0 7 7 0 7 60 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _