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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
35.45
Human Site:
S481
Identified Species:
55.71
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Chimpanzee
Pan troglodytes
XP_515309
740
82400
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Dog
Lupus familis
XP_848865
740
82396
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Rat
Rattus norvegicus
Q641Y8
740
82479
S481
N
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
T481
N
T
L
P
G
A
N
T
P
E
M
W
S
E
A
Frog
Xenopus laevis
A2VD92
740
82328
S481
N
T
R
P
G
G
N
S
A
E
V
W
S
E
A
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
S481
D
T
R
P
G
A
N
S
P
E
M
W
S
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
K481
V
H
P
G
N
H
S
K
E
T
L
S
Q
A
V
Honey Bee
Apis mellifera
XP_392325
733
81819
P483
I
R
P
G
N
N
N
P
E
T
L
S
E
A
V
Nematode Worm
Caenorhab. elegans
P27639
402
45389
R171
R
N
A
L
D
T
S
R
I
K
M
F
V
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
L402
D
S
D
K
R
S
H
L
M
D
L
L
H
A
Q
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
D315
L
A
A
D
Y
L
N
D
P
I
Q
V
Q
V
G
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
L383
W
P
L
D
I
Q
K
L
A
E
S
Y
M
I
N
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
100
N.A.
13.3
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
0
54
0
0
14
0
0
0
0
20
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
7
14
7
0
0
7
0
7
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
14
67
0
0
7
60
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
14
60
7
0
0
0
0
0
0
0
0
7
% G
% His:
0
7
0
0
0
7
7
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
7
7
0
0
0
7
0
% I
% Lys:
0
0
0
7
0
0
7
7
0
7
0
0
0
0
0
% K
% Leu:
7
0
14
7
0
7
0
14
0
0
20
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
60
0
7
0
0
% M
% Asn:
54
7
0
0
14
7
74
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
14
60
0
0
0
7
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
7
0
14
0
7
% Q
% Arg:
7
7
54
0
7
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
7
14
54
0
0
7
14
60
0
0
% S
% Thr:
0
60
0
0
0
7
0
7
0
14
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
7
7
7
7
14
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _