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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX1
All Species:
34.24
Human Site:
S269
Identified Species:
53.81
UniProt:
Q92499
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92499
NP_004930.1
740
82432
S269
P
D
G
Y
I
V
K
S
Q
H
S
G
N
A
Q
Chimpanzee
Pan troglodytes
XP_515309
740
82400
S269
P
D
G
Y
I
V
K
S
Q
H
S
G
N
A
Q
Rhesus Macaque
Macaca mulatta
XP_001090643
740
82473
S269
P
D
G
Y
I
V
K
S
Q
H
S
G
N
A
Q
Dog
Lupus familis
XP_848865
740
82396
S269
S
D
S
Y
V
V
K
S
Q
H
T
G
N
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR5
740
82482
S269
P
D
N
Y
I
V
K
S
Q
H
T
G
N
A
Q
Rat
Rattus norvegicus
Q641Y8
740
82479
S269
P
D
S
Y
V
V
K
S
Q
H
T
G
N
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WU3
740
82466
S269
P
D
G
N
V
V
K
S
Q
H
T
G
N
A
Q
Frog
Xenopus laevis
A2VD92
740
82328
S269
P
D
G
H
V
V
K
S
Q
N
T
G
S
A
Q
Zebra Danio
Brachydanio rerio
XP_684782
740
82395
S269
P
E
G
H
V
V
K
S
S
Q
T
G
S
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNV3
727
80851
P269
P
E
H
S
K
A
N
P
I
T
G
P
A
A
G
Honey Bee
Apis mellifera
XP_392325
733
81819
I271
E
A
I
R
E
N
S
I
N
S
N
Q
T
Q
S
Nematode Worm
Caenorhab. elegans
P27639
402
45389
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84W89
633
67608
R197
I
P
I
L
L
E
G
R
D
L
M
A
C
A
Q
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
K110
I
S
G
H
D
I
P
K
P
I
T
T
F
D
E
Red Bread Mold
Neurospora crassa
Q7S5R1
614
67729
R177
D
P
S
S
S
N
L
R
P
I
M
N
F
S
Q
Conservation
Percent
Protein Identity:
100
99.8
99.5
97.6
N.A.
97.5
97.6
N.A.
N.A.
93.2
89.7
84.8
N.A.
59.7
62.9
22.4
N.A.
Protein Similarity:
100
100
100
99.1
N.A.
99.4
99.5
N.A.
N.A.
97
96
93.7
N.A.
76
78.7
36.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
80
N.A.
N.A.
80
66.6
46.6
N.A.
13.3
0
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
100
86.6
N.A.
20
6.6
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
23.9
23.6
Protein Similarity:
N.A.
N.A.
N.A.
37.1
38.9
40.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
0
0
0
7
7
74
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
54
0
0
7
0
0
0
7
0
0
0
0
7
0
% D
% Glu:
7
14
0
0
7
7
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% F
% Gly:
0
0
47
0
0
0
7
0
0
0
7
60
0
0
7
% G
% His:
0
0
7
20
0
0
0
0
0
47
0
0
0
0
0
% H
% Ile:
14
0
14
0
27
7
0
7
7
14
0
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
60
7
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
7
0
7
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% M
% Asn:
0
0
7
7
0
14
7
0
7
7
7
7
47
0
0
% N
% Pro:
60
14
0
0
0
0
7
7
14
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
54
7
0
7
0
7
67
% Q
% Arg:
0
0
0
7
0
0
0
14
0
0
0
0
0
0
0
% R
% Ser:
7
7
20
14
7
0
7
60
7
7
20
0
14
7
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
47
7
7
0
0
% T
% Val:
0
0
0
0
34
60
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _