KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPH1
All Species:
11.82
Human Site:
Y288
Identified Species:
21.67
UniProt:
Q8WYR4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYR4
NP_543136.1
309
35124
Y288
Y
D
Q
E
E
F
R
Y
D
M
D
E
G
N
I
Chimpanzee
Pan troglodytes
XP_531574
309
35105
Y288
Y
D
Q
E
E
F
H
Y
D
M
D
E
G
N
I
Rhesus Macaque
Macaca mulatta
XP_001105425
309
35135
Y288
Y
D
Q
E
E
F
R
Y
D
V
D
E
G
N
I
Dog
Lupus familis
XP_535597
322
36300
Y300
Y
G
R
D
D
Y
R
Y
D
T
T
D
Q
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIG3
301
34163
E280
T
F
R
Q
E
S
Q
E
N
S
Y
D
I
D
Q
Rat
Rattus norvegicus
Q641X6
483
53170
G395
P
S
M
L
E
K
A
G
N
R
P
K
G
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511551
370
41653
P349
K
E
E
P
Q
E
E
P
E
E
E
D
K
D
D
Chicken
Gallus gallus
XP_416745
338
37606
E317
E
I
R
K
E
G
N
E
E
G
E
E
Y
Q
G
Frog
Xenopus laevis
Q5PPV3
238
27523
K218
K
Y
P
L
P
E
V
K
V
A
D
P
E
G
V
Zebra Danio
Brachydanio rerio
XP_001343012
232
26200
K211
T
I
L
K
W
K
P
K
A
I
T
A
L
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609609
344
38803
E298
G
E
E
A
E
G
E
E
G
G
E
M
E
C
F
Honey Bee
Apis mellifera
XP_001122531
424
48545
P372
L
L
P
P
E
P
V
P
L
Q
E
E
I
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790120
287
30719
A267
Q
E
Q
T
E
E
P
A
E
G
G
E
E
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
93.1
70.8
N.A.
77.6
21.1
N.A.
49.7
52.9
22.3
48.8
N.A.
32.2
32.5
N.A.
44.9
Protein Similarity:
100
99
96.1
82.9
N.A.
85.1
33.3
N.A.
62.1
65.3
38.5
58.2
N.A.
48.8
43.4
N.A.
56.9
P-Site Identity:
100
93.3
93.3
33.3
N.A.
6.6
13.3
N.A.
0
13.3
6.6
0
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
93.3
100
66.6
N.A.
46.6
33.3
N.A.
46.6
40
13.3
26.6
N.A.
26.6
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
24
0
8
8
0
0
0
31
0
31
24
0
24
8
% D
% Glu:
8
24
16
24
70
24
16
24
24
8
31
47
24
0
0
% E
% Phe:
0
8
0
0
0
24
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
0
0
16
0
8
8
24
8
0
31
16
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
8
0
0
16
0
31
% I
% Lys:
16
0
0
16
0
16
0
16
0
0
0
8
8
0
0
% K
% Leu:
8
8
8
16
0
0
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
16
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
16
0
0
0
0
24
0
% N
% Pro:
8
0
16
16
8
8
16
16
0
0
8
8
0
0
0
% P
% Gln:
8
0
31
8
8
0
8
0
0
8
0
0
8
16
8
% Q
% Arg:
0
0
24
0
0
0
24
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
8
0
0
0
8
0
0
0
16
0
% S
% Thr:
16
0
0
8
0
0
0
0
0
8
16
0
0
0
0
% T
% Val:
0
0
0
0
0
0
16
0
8
8
0
0
0
0
24
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
31
8
0
0
0
8
0
31
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _