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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPH1
All Species:
15.76
Human Site:
Y281
Identified Species:
28.89
UniProt:
Q8WYR4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYR4
NP_543136.1
309
35124
Y281
L
R
E
E
S
R
E
Y
D
Q
E
E
F
R
Y
Chimpanzee
Pan troglodytes
XP_531574
309
35105
Y281
L
R
E
E
S
R
E
Y
D
Q
E
E
F
H
Y
Rhesus Macaque
Macaca mulatta
XP_001105425
309
35135
Y281
L
R
E
E
S
R
E
Y
D
Q
E
E
F
R
Y
Dog
Lupus familis
XP_535597
322
36300
Y293
T
R
E
D
S
R
E
Y
G
R
D
D
Y
R
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIG3
301
34163
T273
G
A
D
E
D
V
D
T
F
R
Q
E
S
Q
E
Rat
Rattus norvegicus
Q641X6
483
53170
P388
M
Q
P
Y
L
F
L
P
S
M
L
E
K
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511551
370
41653
K342
E
K
D
E
E
E
P
K
E
E
P
Q
E
E
P
Chicken
Gallus gallus
XP_416745
338
37606
E310
D
A
E
E
E
D
E
E
I
R
K
E
G
N
E
Frog
Xenopus laevis
Q5PPV3
238
27523
K211
T
E
A
P
Y
P
T
K
Y
P
L
P
E
V
K
Zebra Danio
Brachydanio rerio
XP_001343012
232
26200
T204
E
E
E
P
A
M
T
T
I
L
K
W
K
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609609
344
38803
G291
K
I
S
W
Y
G
E
G
E
E
A
E
G
E
E
Honey Bee
Apis mellifera
XP_001122531
424
48545
L365
I
T
P
Y
N
P
D
L
L
P
P
E
P
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790120
287
30719
Q260
A
E
G
D
G
E
T
Q
E
Q
T
E
E
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
93.1
70.8
N.A.
77.6
21.1
N.A.
49.7
52.9
22.3
48.8
N.A.
32.2
32.5
N.A.
44.9
Protein Similarity:
100
99
96.1
82.9
N.A.
85.1
33.3
N.A.
62.1
65.3
38.5
58.2
N.A.
48.8
43.4
N.A.
56.9
P-Site Identity:
100
93.3
100
53.3
N.A.
13.3
6.6
N.A.
6.6
26.6
0
6.6
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
100
86.6
N.A.
46.6
20
N.A.
40
40
0
20
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
0
8
0
0
0
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
16
8
8
16
0
24
0
8
8
0
0
0
% D
% Glu:
16
24
47
47
16
16
47
8
24
16
24
70
24
16
24
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
24
0
0
% F
% Gly:
8
0
8
0
8
8
0
8
8
0
0
0
16
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
0
0
0
0
16
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
16
0
0
16
0
16
0
16
% K
% Leu:
24
0
0
0
8
0
8
8
8
8
16
0
0
0
0
% L
% Met:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
16
16
0
16
8
8
0
16
16
8
8
16
16
% P
% Gln:
0
8
0
0
0
0
0
8
0
31
8
8
0
8
0
% Q
% Arg:
0
31
0
0
0
31
0
0
0
24
0
0
0
24
0
% R
% Ser:
0
0
8
0
31
0
0
0
8
0
0
0
8
0
0
% S
% Thr:
16
8
0
0
0
0
24
16
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
16
16
0
0
31
8
0
0
0
8
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _