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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPH1
All Species:
23.33
Human Site:
T189
Identified Species:
42.78
UniProt:
Q8WYR4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYR4
NP_543136.1
309
35124
T189
Q
H
G
E
Y
R
L
T
D
M
E
R
G
E
E
Chimpanzee
Pan troglodytes
XP_531574
309
35105
T189
Q
H
G
E
Y
R
L
T
D
M
E
R
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001105425
309
35135
T189
Q
H
G
E
Y
R
L
T
D
M
E
R
G
E
E
Dog
Lupus familis
XP_535597
322
36300
T197
Q
H
G
E
Y
R
L
T
D
V
E
R
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIG3
301
34163
T189
Q
H
G
E
Y
R
L
T
D
T
E
R
G
E
E
Rat
Rattus norvegicus
Q641X6
483
53170
S231
L
L
E
V
V
Q
G
S
P
F
T
L
S
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511551
370
41653
A248
Q
H
G
E
Y
I
P
A
D
Q
D
R
G
E
E
Chicken
Gallus gallus
XP_416745
338
37606
S189
Q
H
G
E
Y
I
Q
S
E
E
D
K
G
E
E
Frog
Xenopus laevis
Q5PPV3
238
27523
E138
F
A
N
G
D
I
Y
E
G
E
W
L
E
D
K
Zebra Danio
Brachydanio rerio
XP_001343012
232
26200
T132
G
A
Y
T
Y
H
D
T
G
S
Q
Y
V
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609609
344
38803
R196
A
V
F
S
F
N
N
R
Y
L
L
L
G
Y
F
Honey Bee
Apis mellifera
XP_001122531
424
48545
V291
Q
H
G
H
Y
V
H
V
K
D
P
D
Y
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790120
287
30719
E187
V
S
Q
Y
N
P
A
E
E
A
I
A
A
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
93.1
70.8
N.A.
77.6
21.1
N.A.
49.7
52.9
22.3
48.8
N.A.
32.2
32.5
N.A.
44.9
Protein Similarity:
100
99
96.1
82.9
N.A.
85.1
33.3
N.A.
62.1
65.3
38.5
58.2
N.A.
48.8
43.4
N.A.
56.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
66.6
53.3
0
13.3
N.A.
6.6
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
73.3
80
13.3
20
N.A.
20
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
0
8
8
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
47
8
16
8
0
16
0
% D
% Glu:
0
0
8
54
0
0
0
16
16
16
39
0
8
54
62
% E
% Phe:
8
0
8
0
8
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
8
0
62
8
0
0
8
0
16
0
0
0
62
8
0
% G
% His:
0
62
0
8
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
24
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% K
% Leu:
8
8
0
0
0
0
39
0
0
8
8
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
8
0
8
0
0
0
0
% P
% Gln:
62
0
8
0
0
8
8
0
0
8
8
0
0
8
16
% Q
% Arg:
0
0
0
0
0
39
0
8
0
0
0
47
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
16
0
8
0
0
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
47
0
8
8
0
0
0
8
% T
% Val:
8
8
0
8
8
8
0
8
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
8
70
0
8
0
8
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _