KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
31.21
Human Site:
Y443
Identified Species:
68.67
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
Y443
D
L
E
E
F
R
S
Y
L
E
K
R
F
D
F
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
Y443
D
L
E
E
F
R
S
Y
L
E
K
R
F
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
Y424
D
L
E
E
F
R
N
Y
L
E
K
R
F
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
Y443
D
L
E
E
F
R
N
Y
L
E
K
R
F
D
F
Rat
Rattus norvegicus
NP_001099335
773
86341
Y443
D
L
E
E
F
R
N
Y
L
E
K
R
F
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
Y445
D
L
E
D
F
R
R
Y
L
E
K
R
F
D
F
Frog
Xenopus laevis
NP_001085043
772
87175
Y442
N
L
E
D
F
R
S
Y
L
E
K
R
F
D
F
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
Y452
E
I
E
D
F
R
S
Y
L
E
K
C
F
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
K320
N
A
R
R
K
F
T
K
N
R
K
H
I
K
N
Honey Bee
Apis mellifera
XP_397444
627
71159
R305
F
T
K
N
K
K
H
R
K
Q
L
E
R
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
H95
G
K
K
K
N
R
V
H
I
C
E
D
D
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
73.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
20
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
55
0
0
28
0
0
0
0
0
0
0
10
10
73
0
% D
% Glu:
10
0
73
46
0
0
0
0
0
73
10
10
0
0
0
% E
% Phe:
10
0
0
0
73
10
0
0
0
0
0
0
73
0
73
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
0
10
19
10
19
10
0
10
10
0
82
0
0
10
0
% K
% Leu:
0
64
0
0
0
0
0
0
73
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
10
10
0
28
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
82
10
10
0
10
0
64
10
0
0
% R
% Ser:
0
0
0
0
0
0
37
0
0
0
0
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _