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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
25.15
Human Site:
S760
Identified Species:
55.33
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
S760
P
K
M
S
I
V
A
S
A
Q
P
G
G
E
P
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
S760
P
K
M
S
I
V
A
S
A
Q
P
G
G
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
A758
A
G
T
G
S
S
A
A
R
D
T
T
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
S760
P
K
M
S
I
V
A
S
A
Q
P
G
G
E
P
Rat
Rattus norvegicus
NP_001099335
773
86341
S760
P
K
M
S
I
V
A
S
A
Q
P
G
G
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
S762
P
K
M
T
I
V
E
S
A
Q
P
G
S
E
P
Frog
Xenopus laevis
NP_001085043
772
87175
S759
P
K
M
T
I
V
E
S
A
Q
P
G
S
E
P
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
S769
P
K
M
T
I
M
E
S
A
Q
P
G
S
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
P630
P
P
S
D
V
D
L
P
T
S
S
G
S
N
L
Honey Bee
Apis mellifera
XP_397444
627
71159
P615
K
F
V
P
P
D
L
P
T
G
S
A
A
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
E405
K
K
Q
G
E
D
G
E
Q
E
M
E
E
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
86.6
N.A.
6.6
N.A.
100
100
N.A.
N.A.
80
80
73.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
13.3
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
20
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
46
10
64
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
28
0
0
0
10
0
0
0
10
10
% D
% Glu:
0
0
0
0
10
0
28
10
0
10
0
10
10
55
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
19
0
0
10
0
0
10
0
73
37
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
73
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
19
% L
% Met:
0
0
64
0
0
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
73
10
0
10
10
0
0
19
0
0
64
0
0
0
55
% P
% Gln:
0
0
10
0
0
0
0
0
10
64
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% R
% Ser:
0
0
10
37
10
10
0
64
0
10
19
0
37
0
10
% S
% Thr:
0
0
10
28
0
0
0
0
19
0
10
10
0
0
0
% T
% Val:
0
0
10
0
10
55
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _