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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
31.82
Human Site:
S493
Identified Species:
70
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
S493
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
S493
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
S474
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
S493
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Rat
Rattus norvegicus
NP_001099335
773
86341
S493
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
S495
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Frog
Xenopus laevis
NP_001085043
772
87175
S492
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
S502
N
Q
K
L
I
T
L
S
V
Q
D
A
P
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
G367
E
W
I
M
N
P
N
G
K
S
F
V
C
I
L
Honey Bee
Apis mellifera
XP_397444
627
71159
L352
G
K
S
Y
V
C
I
L
H
E
Y
V
Q
H
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
D142
T
K
A
V
K
H
K
D
R
P
Q
F
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
6.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
73
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
73
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
73
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
19
73
0
10
0
10
0
10
0
0
0
0
0
73
% K
% Leu:
0
0
0
73
0
0
73
10
0
0
0
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
10
0
0
82
0
0
% P
% Gln:
0
73
0
0
0
0
0
0
0
73
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
73
0
10
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
73
0
0
0
0
0
0
0
73
0
% T
% Val:
0
0
0
10
10
0
0
0
73
0
0
19
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _