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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
16.06
Human Site:
S385
Identified Species:
35.33
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
S385
P
V
K
P
L
S
R
S
A
E
L
E
F
P
L
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
S385
P
V
K
P
L
S
R
S
A
E
L
E
F
P
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
A385
S
I
G
A
D
S
G
A
L
D
E
K
D
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
S385
P
V
K
P
L
G
R
S
A
E
L
D
F
P
L
Rat
Rattus norvegicus
NP_001099335
773
86341
S385
P
V
K
P
L
G
R
S
A
E
L
D
F
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
S387
P
I
K
H
I
D
K
S
S
E
L
D
C
Q
T
Frog
Xenopus laevis
NP_001085043
772
87175
D387
S
S
S
T
K
S
S
D
T
S
H
N
S
E
E
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
G376
P
V
K
S
G
E
E
G
I
S
L
E
R
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
E284
V
N
E
N
T
Q
K
E
S
I
T
P
E
Q
L
Honey Bee
Apis mellifera
XP_397444
627
71159
E269
A
A
H
S
L
D
S
E
Q
L
R
N
Y
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
P59
N
L
P
D
Q
P
S
P
A
A
G
G
A
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
20
N.A.
86.6
86.6
N.A.
N.A.
33.3
6.6
33.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
46.6
N.A.
93.3
93.3
N.A.
N.A.
66.6
6.6
33.3
N.A.
26.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
10
46
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
0
0
10
10
19
0
10
0
10
0
28
10
10
19
% D
% Glu:
0
0
10
0
0
10
10
19
0
46
10
28
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% F
% Gly:
0
0
10
0
10
19
10
10
0
0
10
10
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
19
0
0
10
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
55
0
10
0
19
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
0
46
0
0
0
10
10
55
0
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
0
0
0
0
0
19
0
0
0
% N
% Pro:
55
0
10
37
0
10
0
10
0
0
0
10
0
46
0
% P
% Gln:
0
0
0
0
10
10
0
0
10
0
0
0
0
19
10
% Q
% Arg:
0
0
0
0
0
0
37
0
0
0
10
0
10
0
0
% R
% Ser:
19
10
10
19
0
37
28
46
19
19
0
0
10
0
0
% S
% Thr:
0
0
0
10
10
0
0
0
10
0
10
0
0
0
10
% T
% Val:
10
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _