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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
14.55
Human Site:
S367
Identified Species:
32
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
S367
D
N
E
E
R
E
Q
S
S
D
L
T
P
S
G
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
S367
D
N
E
E
R
E
Q
S
S
D
L
T
P
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
A367
V
K
P
L
S
R
S
A
E
L
E
F
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
N367
D
N
E
E
R
E
Q
N
C
D
L
A
P
S
G
Rat
Rattus norvegicus
NP_001099335
773
86341
S367
D
N
E
E
R
E
Q
S
C
D
L
A
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
N369
E
N
E
E
R
E
Q
N
N
D
I
T
P
N
G
Frog
Xenopus laevis
NP_001085043
772
87175
S369
D
N
D
I
K
E
Q
S
N
D
V
T
S
A
L
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
N358
E
Q
E
E
R
E
Q
N
G
E
V
T
P
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
T266
K
T
Q
P
D
G
I
T
A
L
M
P
A
A
K
Honey Bee
Apis mellifera
XP_397444
627
71159
S251
A
E
V
C
S
L
P
S
A
K
I
E
T
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
D41
D
M
K
T
E
P
P
D
T
C
H
T
Q
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
80
86.6
N.A.
N.A.
66.6
46.6
46.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
13.3
N.A.
86.6
86.6
N.A.
N.A.
100
80
80
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
19
0
0
19
10
19
10
% A
% Cys:
0
0
0
10
0
0
0
0
19
10
0
0
0
0
0
% C
% Asp:
55
0
10
0
10
0
0
10
0
55
0
0
0
10
0
% D
% Glu:
19
10
55
55
10
64
0
0
10
10
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
19
0
0
10
0
% I
% Lys:
10
10
10
0
10
0
0
0
0
10
0
0
0
0
10
% K
% Leu:
0
0
0
10
0
10
0
0
0
19
37
0
0
10
19
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
55
0
0
0
0
0
28
19
0
0
0
0
10
0
% N
% Pro:
0
0
10
10
0
10
19
0
0
0
0
10
64
0
0
% P
% Gln:
0
10
10
0
0
0
64
0
0
0
0
0
10
0
10
% Q
% Arg:
0
0
0
0
55
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
0
10
46
19
0
0
0
10
37
0
% S
% Thr:
0
10
0
10
0
0
0
10
10
0
0
55
10
10
0
% T
% Val:
10
0
10
0
0
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _