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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT1
All Species:
22.42
Human Site:
S315
Identified Species:
49.33
UniProt:
Q8WYJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYJ6
NP_443070.1
367
41971
S315
R
S
K
L
S
R
Q
S
A
T
E
I
P
L
P
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
P332
K
G
Q
L
T
K
S
P
L
A
Q
M
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001110653
409
46509
S357
R
S
K
L
S
R
Q
S
A
T
E
I
P
L
P
Dog
Lupus familis
XP_547019
435
48969
S383
R
S
K
L
S
R
Q
S
A
T
E
I
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P42209
366
42001
S314
R
S
K
L
S
R
Q
S
A
T
E
I
P
L
P
Rat
Rattus norvegicus
Q5EB96
366
42039
S314
R
S
K
L
S
R
Q
S
A
T
E
I
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518204
427
48081
S377
R
S
K
L
S
R
Q
S
A
T
E
F
P
L
P
Chicken
Gallus gallus
Q5ZMH1
349
40206
L303
E
N
F
R
S
E
R
L
K
R
T
G
K
P
V
Frog
Xenopus laevis
Q63ZQ1
352
40432
R299
D
L
H
Y
E
N
F
R
S
E
R
L
K
K
G
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
N304
V
V
E
V
E
N
P
N
H
C
E
F
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
V323
E
R
D
S
S
S
Q
V
V
S
N
S
V
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.4
89.2
80.9
N.A.
95.6
94.8
N.A.
75.6
54.2
56.1
40.8
N.A.
55
N.A.
N.A.
N.A.
Protein Similarity:
100
63.3
89.2
82.9
N.A.
98
97.8
N.A.
80.5
74.1
74.3
59.4
N.A.
74.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
6.6
0
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
93.3
20
13.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
55
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
10
0
19
10
0
0
0
10
64
0
10
10
10
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
19
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
19
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% I
% Lys:
10
0
55
0
0
10
0
0
10
0
0
0
19
10
0
% K
% Leu:
0
10
0
64
0
0
0
10
10
0
0
10
0
73
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
19
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
0
0
55
10
55
% P
% Gln:
0
0
10
0
0
0
64
0
0
0
10
0
0
0
0
% Q
% Arg:
55
10
0
10
0
55
10
10
0
10
10
0
0
0
0
% R
% Ser:
0
55
0
10
73
10
10
55
10
10
0
10
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
55
10
0
0
0
0
% T
% Val:
10
10
0
10
0
0
0
10
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _