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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARNTL2 All Species: 7.27
Human Site: S539 Identified Species: 20
UniProt: Q8WYA1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WYA1 NP_064568.3 636 70887 S539 S S S Y L D D S S P T G L M K
Chimpanzee Pan troglodytes XP_520811 745 81792 S649 S S S Y L D D S S P T G L M K
Rhesus Macaque Macaca mulatta XP_001103493 599 66864 P504 S Y L D D L S P T N L M K D T
Dog Lupus familis XP_543750 630 70803 S534 S P S L D D S S P T D L M K D
Cat Felis silvestris
Mouse Mus musculus Q2VPD4 579 64380 V484 D A S P S E E V R D D C S V N
Rat Rattus norvegicus Q9EPW1 626 68597 R508 E E I M E I H R I R G S S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8QGQ7 622 69113 P524 S P P G E L S P S H L L R K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9DG12 737 80954 T520 D I Y T G I S T S E K K M M V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61734 413 47551 E318 F I S R H S G E G K F L F I D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.7 83.1 84.1 N.A. 65.5 50.9 N.A. N.A. 64.1 N.A. 29 N.A. 29.7 N.A. N.A. N.A.
Protein Similarity: 100 79.8 87.1 90.4 N.A. 73.4 67.3 N.A. N.A. 76 N.A. 48.2 N.A. 42.6 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 26.6 N.A. 6.6 0 N.A. N.A. 13.3 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 33.3 N.A. 33.3 0 N.A. N.A. 13.3 N.A. 26.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 23 0 0 12 23 34 23 0 0 12 23 0 0 12 23 % D
% Glu: 12 12 0 0 23 12 12 12 0 12 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 12 0 12 0 0 % F
% Gly: 0 0 0 12 12 0 12 0 12 0 12 23 0 0 0 % G
% His: 0 0 0 0 12 0 12 0 0 12 0 0 0 0 0 % H
% Ile: 0 23 12 0 0 23 0 0 12 0 0 0 0 12 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 12 12 12 12 23 23 % K
% Leu: 0 0 12 12 23 23 0 0 0 0 23 34 23 0 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 12 23 34 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 12 % N
% Pro: 0 23 12 12 0 0 0 23 12 23 0 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 0 0 0 12 12 12 0 0 12 0 0 % R
% Ser: 56 23 56 0 12 12 45 34 45 0 0 12 23 0 23 % S
% Thr: 0 0 0 12 0 0 0 12 12 12 23 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 12 23 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _