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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP4
All Species:
5.15
Human Site:
T222
Identified Species:
14.17
UniProt:
Q8WY91
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY91
NP_001157828.1
577
62890
T222
G
I
S
M
D
D
F
T
P
P
G
S
G
A
C
Chimpanzee
Pan troglodytes
XP_516210
686
73181
T331
G
I
S
M
D
D
F
T
P
P
G
S
G
A
C
Rhesus Macaque
Macaca mulatta
XP_001093438
442
47909
H101
C
K
F
I
G
S
L
H
S
Y
S
F
S
S
K
Dog
Lupus familis
XP_543333
632
68437
F276
S
G
I
S
K
D
D
F
T
P
P
G
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3Z3
569
62552
P218
I
S
M
D
D
F
T
P
P
G
S
G
A
C
K
Rat
Rattus norvegicus
Q642B6
569
62388
P218
I
S
M
D
D
F
T
P
P
G
S
G
A
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513078
670
74072
S229
L
H
S
Y
S
F
S
S
K
H
T
R
E
R
S
Chicken
Gallus gallus
Q5ZHN5
413
46679
W71
P
D
S
L
D
V
R
W
G
I
R
Y
L
K
H
Frog
Xenopus laevis
Q0IHI7
372
42347
L31
V
S
F
Y
P
F
P
L
H
D
R
G
R
L
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
74.8
77.3
N.A.
83.3
83.8
N.A.
44.9
22.1
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.6
75
82.2
N.A.
89.7
89.9
N.A.
57.4
39.5
36.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
13.3
13.3
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
13.3
13.3
N.A.
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
23
23
12
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
23
23
% C
% Asp:
0
12
0
23
56
34
12
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
23
0
0
45
23
12
0
0
0
12
0
0
0
% F
% Gly:
23
12
0
0
12
0
0
0
12
23
23
45
23
12
0
% G
% His:
0
12
0
0
0
0
0
12
12
12
0
0
0
0
12
% H
% Ile:
23
23
12
12
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
0
0
12
0
0
0
12
0
0
0
0
12
34
% K
% Leu:
12
0
0
12
0
0
12
12
0
0
0
0
12
12
0
% L
% Met:
0
0
23
23
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
12
0
12
23
45
34
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
23
12
12
12
0
% R
% Ser:
12
34
45
12
12
12
12
12
12
0
34
23
23
12
12
% S
% Thr:
0
0
0
0
0
0
23
23
12
0
12
0
0
0
0
% T
% Val:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
23
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _