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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXD4L4
All Species:
9.39
Human Site:
S323
Identified Species:
20.67
UniProt:
Q8WXT5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXT5
NP_001092749.1
416
45892
S323
R
H
R
E
A
D
A
S
L
S
A
L
R
V
L
Chimpanzee
Pan troglodytes
NP_001009014
413
45421
S319
R
H
R
E
A
D
A
S
L
S
A
L
R
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60688
444
48029
I322
R
G
C
A
S
F
T
I
E
S
I
M
Q
G
V
Rat
Rattus norvegicus
Q63245
101
11924
T25
Q
S
P
Q
K
K
L
T
L
S
G
I
C
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516678
728
77542
I451
S
S
F
S
I
E
S
I
M
R
G
N
K
A
E
Chicken
Gallus gallus
P79772
394
40977
S307
S
S
L
G
A
A
G
S
I
V
K
S
E
P
S
Frog
Xenopus laevis
Q9DEN4
371
40000
A284
S
S
L
S
S
T
A
A
S
I
I
K
S
E
P
Zebra Danio
Brachydanio rerio
NP_571365
371
40457
I287
S
L
S
T
A
S
I
I
K
S
E
P
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02361
456
49036
T316
P
Y
A
F
D
V
A
T
V
A
S
A
A
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496411
333
37274
H257
P
F
P
P
R
M
M
H
P
M
A
N
I
P
M
Sea Urchin
Strong. purpuratus
XP_001188749
401
43606
P320
L
L
N
G
S
T
A
P
P
S
T
T
V
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
N.A.
N.A.
N.A.
50
21.6
N.A.
31.8
39.1
36.5
36
N.A.
30.7
N.A.
30.5
32.2
Protein Similarity:
100
96.8
N.A.
N.A.
N.A.
58.3
23
N.A.
38.7
48.7
48.3
48
N.A.
42.1
N.A.
45.6
44.4
P-Site Identity:
100
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
13.3
6.6
13.3
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
40
40
N.A.
26.6
20
20
13.3
N.A.
46.6
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
37
10
46
10
0
10
28
10
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
19
0
10
0
0
10
0
10
0
10
19
10
% E
% Phe:
0
10
10
10
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
19
0
0
10
0
0
0
19
0
0
19
0
% G
% His:
0
19
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
28
10
10
19
10
10
0
10
% I
% Lys:
0
0
0
0
10
10
0
0
10
0
10
10
10
0
0
% K
% Leu:
10
19
19
0
0
0
10
0
28
0
0
19
0
0
19
% L
% Met:
0
0
0
0
0
10
10
0
10
10
0
10
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
19
0
0
0
% N
% Pro:
19
0
19
10
0
0
0
10
19
0
0
10
0
19
10
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
28
0
19
0
10
0
0
0
0
10
0
0
19
0
10
% R
% Ser:
37
37
10
19
28
10
10
28
10
55
10
10
19
10
19
% S
% Thr:
0
0
0
10
0
19
10
19
0
0
10
10
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
10
10
0
0
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _