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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS4
All Species:
10.91
Human Site:
S61
Identified Species:
30
UniProt:
Q8WXH5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXH5
NP_543143.1
440
50623
S61
G
I
E
K
T
E
V
S
L
R
N
Q
E
R
K
Chimpanzee
Pan troglodytes
XP_509960
440
50619
S61
G
I
E
K
T
E
V
S
L
R
N
Q
E
R
K
Rhesus Macaque
Macaca mulatta
XP_001087843
440
50662
S61
G
I
E
K
T
E
V
S
L
R
N
R
E
R
K
Dog
Lupus familis
XP_531810
536
61259
G148
K
F
G
R
T
R
S
G
L
Q
R
R
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZA6
436
49929
R60
E
N
V
E
I
P
L
R
S
Q
E
R
Q
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107230
528
58598
A117
R
D
S
Y
S
R
H
A
P
W
S
G
K
K
R
Tiger Blowfish
Takifugu rubipres
NP_001116333
550
60455
S133
R
S
G
R
V
R
G
S
G
N
R
R
D
R
R
Fruit Fly
Dros. melanogaster
NP_724096
633
68884
A73
I
I
I
K
I
Q
L
A
K
M
E
N
G
N
P
Honey Bee
Apis mellifera
XP_624419
475
53901
C71
F
K
Q
Q
E
A
C
C
S
S
S
G
S
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
43.8
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
N.A.
43.1
40.9
28.4
32.8
N.A.
N.A.
Protein Similarity:
100
100
99.3
59.1
N.A.
92.7
N.A.
N.A.
N.A.
N.A.
N.A.
56.8
54.9
42.3
45.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
40
40
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
12
0
34
12
12
34
0
0
0
0
23
0
45
0
0
% E
% Phe:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
23
0
0
0
12
12
12
0
0
23
12
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
12
45
12
0
23
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
45
0
0
0
0
12
0
0
0
12
12
34
% K
% Leu:
0
0
0
0
0
0
23
0
45
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
12
34
12
0
12
12
% N
% Pro:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% P
% Gln:
0
0
12
12
0
12
0
0
0
23
0
23
12
0
0
% Q
% Arg:
23
0
0
23
0
34
0
12
0
34
23
45
0
56
34
% R
% Ser:
0
12
12
0
12
0
12
45
23
12
23
0
12
12
12
% S
% Thr:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
12
0
34
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _