KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS4
All Species:
14.55
Human Site:
S38
Identified Species:
40
UniProt:
Q8WXH5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXH5
NP_543143.1
440
50623
S38
V
W
S
G
K
K
L
S
W
S
K
K
S
E
S
Chimpanzee
Pan troglodytes
XP_509960
440
50619
S38
V
W
S
G
K
K
L
S
W
S
K
K
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001087843
440
50662
S38
V
W
S
G
K
K
L
S
W
S
K
K
S
E
S
Dog
Lupus familis
XP_531810
536
61259
K125
A
P
W
G
G
K
K
K
H
S
C
S
T
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZA6
436
49929
S37
S
G
K
K
L
S
W
S
K
K
S
E
S
C
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107230
528
58598
T94
V
P
Q
I
L
E
I
T
V
E
Q
D
A
D
D
Tiger Blowfish
Takifugu rubipres
NP_001116333
550
60455
K110
A
P
W
G
G
K
K
K
H
S
C
S
T
K
T
Fruit Fly
Dros. melanogaster
NP_724096
633
68884
T50
L
Q
V
E
E
I
L
T
E
A
T
V
S
A
A
Honey Bee
Apis mellifera
XP_624419
475
53901
N48
S
Q
P
I
E
T
Q
N
S
K
Q
I
C
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
43.8
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
N.A.
43.1
40.9
28.4
32.8
N.A.
N.A.
Protein Similarity:
100
100
99.3
59.1
N.A.
92.7
N.A.
N.A.
N.A.
N.A.
N.A.
56.8
54.9
42.3
45.4
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
20
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
40
46.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
0
0
0
0
12
0
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
23
0
12
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
12
% D
% Glu:
0
0
0
12
23
12
0
0
12
12
0
12
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
56
23
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% H
% Ile:
0
0
0
23
0
12
12
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
12
12
34
56
23
23
12
23
34
34
0
23
0
% K
% Leu:
12
0
0
0
23
0
45
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% N
% Pro:
0
34
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
23
12
0
0
0
12
0
0
0
23
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
0
34
0
0
12
0
45
12
56
12
23
56
12
45
% S
% Thr:
0
0
0
0
0
12
0
23
0
0
12
0
23
0
23
% T
% Val:
45
0
12
0
0
0
0
0
12
0
0
12
0
0
0
% V
% Trp:
0
34
23
0
0
0
12
0
34
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _