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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAB3
All Species:
26.36
Human Site:
Y506
Identified Species:
64.44
UniProt:
Q8WWW8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWW8
NP_001075042.1
586
65589
Y506
S
R
E
D
E
E
S
Y
I
E
M
E
E
H
R
Chimpanzee
Pan troglodytes
XP_529211
586
65556
Y506
S
R
E
D
E
E
S
Y
I
E
M
E
E
H
R
Rhesus Macaque
Macaca mulatta
XP_001095912
586
65776
Y506
S
R
E
E
E
E
S
Y
I
E
M
E
E
H
R
Dog
Lupus familis
XP_549381
622
68656
Y542
S
R
E
E
E
E
S
Y
I
Q
M
G
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSM5
595
67822
Y515
E
E
E
E
E
E
K
Y
I
Q
M
E
E
Y
G
Rat
Rattus norvegicus
Q9EQH1
665
73310
N578
E
N
Y
V
P
M
Q
N
P
V
S
A
S
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509543
623
69506
Y543
S
G
E
E
E
E
S
Y
I
Q
M
Q
E
H
R
Chicken
Gallus gallus
XP_426275
601
66883
Y521
S
G
E
E
E
E
S
Y
I
H
M
E
E
H
R
Frog
Xenopus laevis
NP_001089201
691
76011
G602
T
E
D
P
G
L
F
G
N
S
S
L
D
E
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ9
878
95517
T748
A
F
F
H
E
T
R
T
L
P
R
Q
Q
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
41.6
N.A.
76.6
33
N.A.
63.2
66.5
28.5
N.A.
N.A.
23
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.4
51.9
N.A.
85.5
50.8
N.A.
73
77.3
47.4
N.A.
N.A.
36.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
53.3
0
N.A.
73.3
80
0
N.A.
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
0
N.A.
93.3
86.6
20
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
20
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
20
20
70
50
80
70
0
0
0
30
0
50
70
10
0
% E
% Phe:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
10
0
0
10
0
0
0
10
0
0
30
% G
% His:
0
0
0
10
0
0
0
0
0
10
0
0
0
60
0
% H
% Ile:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
70
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
10
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
30
0
20
10
0
0
% Q
% Arg:
0
40
0
0
0
0
10
0
0
0
10
0
0
0
60
% R
% Ser:
60
0
0
0
0
0
60
0
0
10
20
0
10
0
0
% S
% Thr:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
70
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _