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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAB3 All Species: 18.79
Human Site: T148 Identified Species: 45.93
UniProt: Q8WWW8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWW8 NP_001075042.1 586 65589 T148 S S A S S L L T A H A A S S S
Chimpanzee Pan troglodytes XP_529211 586 65556 T148 S S A S S L L T A H A A S S S
Rhesus Macaque Macaca mulatta XP_001095912 586 65776 T148 S S A S S L H T A H A A S S S
Dog Lupus familis XP_549381 622 68656 Y184 N P D V L E Y Y R N K H S S K
Cat Felis silvestris
Mouse Mus musculus Q8BSM5 595 67822 T148 S P A S S L H T V H V A N S A
Rat Rattus norvegicus Q9EQH1 665 73310 S150 S P A E F S S S Q H L L R E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509543 623 69506 F173 S R D T D P S F S G D N S A A
Chicken Gallus gallus XP_426275 601 66883 T148 S P A A S T H T S R I A D P S
Frog Xenopus laevis NP_001089201 691 76011 T218 D C N D N V A T H K G S S A Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ9 878 95517 N195 P M P S N A G N N N S D S V Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.7 41.6 N.A. 76.6 33 N.A. 63.2 66.5 28.5 N.A. N.A. 23 N.A. N.A. N.A.
Protein Similarity: 100 100 98.4 51.9 N.A. 85.5 50.8 N.A. 73 77.3 47.4 N.A. N.A. 36.9 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 60 20 N.A. 13.3 40 13.3 N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 73.3 26.6 N.A. 40 53.3 40 N.A. N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 10 0 10 10 0 30 0 30 50 0 20 20 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 20 10 10 0 0 0 0 0 10 10 10 0 0 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 30 0 10 50 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % K
% Leu: 0 0 0 0 10 40 20 0 0 0 10 10 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 20 0 0 10 10 20 0 10 10 0 0 % N
% Pro: 10 40 10 0 0 10 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 10 10 0 0 10 0 10 % R
% Ser: 70 30 0 50 50 10 20 10 20 0 10 10 70 50 40 % S
% Thr: 0 0 0 10 0 10 0 60 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 10 0 0 10 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _