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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEU4
All Species:
8.48
Human Site:
Y447
Identified Species:
26.67
UniProt:
Q8WWR8
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WWR8
NP_542779.2
484
51572
Y447
E
S
G
A
R
T
S
Y
D
E
I
S
F
C
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095081
484
51492
Y447
E
S
G
A
R
T
S
Y
D
E
I
S
F
C
T
Dog
Lupus familis
XP_852062
389
41377
I355
A
R
V
S
Y
E
E
I
S
F
C
M
F
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZL1
478
52408
Y441
E
S
G
T
R
T
S
Y
E
D
I
S
F
C
L
Rat
Rattus norvegicus
Q99PW5
418
46962
L384
G
Q
G
L
F
A
C
L
F
E
C
G
E
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513020
509
56992
E460
V
A
F
A
C
L
Y
E
N
G
T
K
S
S
Y
Chicken
Gallus gallus
XP_428099
556
60763
F496
S
A
C
E
E
I
A
F
C
L
F
T
L
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018384
429
48499
F395
T
A
Y
D
E
I
S
F
C
I
F
T
L
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.2
53.9
N.A.
71.2
39.8
N.A.
53
23.2
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
96.2
60.7
N.A.
76.4
53.5
N.A.
64.2
33.6
N.A.
59.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
73.3
13.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
13.3
N.A.
86.6
13.3
N.A.
20
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
38
0
38
0
13
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
13
0
13
0
13
0
25
0
25
0
0
38
0
% C
% Asp:
0
0
0
13
0
0
0
0
25
13
0
0
0
0
0
% D
% Glu:
38
0
0
13
25
13
13
13
13
38
0
0
13
0
13
% E
% Phe:
0
0
13
0
13
0
0
25
13
13
25
0
50
0
0
% F
% Gly:
13
0
50
0
0
0
0
0
0
13
0
13
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
25
0
13
0
13
38
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
0
0
0
13
0
13
0
13
0
13
0
0
25
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
13
0
0
38
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
13
38
0
13
0
0
50
0
13
0
0
38
13
25
0
% S
% Thr:
13
0
0
13
0
38
0
0
0
0
13
25
0
0
38
% T
% Val:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
13
0
13
38
0
0
0
0
0
13
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _