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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCFD1
All Species:
37.58
Human Site:
Y421
Identified Species:
55.11
UniProt:
Q8WVM8
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVM8
NP_057190.2
642
72380
Y421
K
A
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Chimpanzee
Pan troglodytes
XP_509885
713
80661
Y492
K
A
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001107671
704
79791
K494
T
A
V
L
E
H
I
K
A
R
K
L
D
V
Y
Dog
Lupus familis
XP_537403
636
71870
Y415
K
A
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRF7
639
72304
Y418
K
A
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Rat
Rattus norvegicus
Q62991
637
72244
Y416
K
A
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512483
639
72142
Y418
K
T
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Chicken
Gallus gallus
XP_421224
720
80613
Y499
K
T
R
K
L
D
V
Y
F
E
Y
E
E
K
I
Frog
Xenopus laevis
NP_001086026
632
71276
Y411
K
T
R
K
L
D
V
Y
F
E
Y
E
E
K
L
Zebra Danio
Brachydanio rerio
NP_878281
632
71526
Y411
K
S
R
K
L
D
V
Y
F
E
Y
E
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24179
657
74488
F405
K
A
R
R
L
D
S
F
F
E
I
E
E
K
V
Honey Bee
Apis mellifera
XP_394325
629
71709
F404
K
S
R
R
L
D
T
F
F
E
L
E
E
K
I
Nematode Worm
Caenorhab. elegans
NP_001122697
689
76498
S437
K
E
R
K
L
D
V
S
L
S
S
S
K
S
C
Sea Urchin
Strong. purpuratus
XP_001191223
651
73407
L403
K
L
D
V
Y
F
E
L
E
E
K
L
M
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL48
627
69132
A411
I
D
R
T
E
L
M
A
A
L
K
G
K
G
T
Baker's Yeast
Sacchar. cerevisiae
P22213
666
74660
F419
E
S
K
S
L
D
T
F
F
E
V
E
Q
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
87.5
98.1
N.A.
96.1
95.3
N.A.
94.8
83.8
88.9
86.9
N.A.
56.3
58.8
43.9
65.7
Protein Similarity:
100
90
87.9
98.5
N.A.
97.5
97
N.A.
96.4
86.8
93.7
93.3
N.A.
74.5
76.1
62.9
80
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
93.3
93.3
86.6
86.6
N.A.
66.6
66.6
40
13.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
86.6
86.6
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.3
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.9
55.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
44
0
0
0
0
0
7
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
7
0
0
82
0
0
0
0
0
0
7
7
0
% D
% Glu:
7
7
0
0
13
0
7
0
7
82
0
75
69
0
0
% E
% Phe:
0
0
0
0
0
7
0
19
75
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
50
% I
% Lys:
82
0
7
63
0
0
0
7
0
0
19
0
13
69
7
% K
% Leu:
0
7
0
7
82
7
0
7
7
7
7
13
0
0
13
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
82
13
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
19
0
7
0
0
7
7
0
7
7
7
0
13
0
% S
% Thr:
7
19
0
7
0
0
13
0
0
0
0
0
0
0
7
% T
% Val:
0
0
7
7
0
0
63
0
0
0
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
57
0
0
57
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _