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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
9.7
Human Site:
S130
Identified Species:
19.39
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
S130
S
D
G
G
S
H
H
S
E
A
E
G
S
E
K
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
A90
R
S
D
N
R
S
E
A
S
E
R
S
D
H
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
S130
S
D
G
G
S
H
H
S
E
A
E
G
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
S130
S
D
E
G
S
R
H
S
E
A
E
G
S
E
K
Rat
Rattus norvegicus
Q641X2
678
76939
A142
E
G
S
H
H
S
E
A
E
G
S
E
K
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
Chicken
Gallus gallus
XP_413803
627
71376
H111
H
S
A
S
E
A
A
H
D
D
E
E
D
E
R
Frog
Xenopus laevis
Q52KV5
703
80388
E162
K
S
D
Q
S
D
E
E
E
K
M
Q
N
S
D
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
D130
S
D
A
T
M
H
S
D
N
E
H
S
M
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
R159
R
S
G
S
A
R
S
R
K
S
G
S
A
Q
S
Honey Bee
Apis mellifera
XP_624295
603
67203
T87
R
H
S
S
I
G
S
T
H
S
Q
K
S
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
E75
E
E
G
E
G
E
Y
E
E
M
V
E
G
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
0
N.A.
100
N.A.
86.6
6.6
N.A.
0
13.3
13.3
20
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
13.3
N.A.
100
N.A.
86.6
20
N.A.
0
26.6
20
26.6
N.A.
40
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
9
17
0
25
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
17
0
0
9
0
9
9
9
0
0
17
0
9
% D
% Glu:
17
9
9
9
9
9
25
17
50
17
34
25
0
42
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
34
25
9
9
0
0
0
9
9
25
9
9
9
% G
% His:
9
9
0
9
9
25
25
9
9
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
9
0
9
9
0
25
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
9
9
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
9
9
0
9
9
% Q
% Arg:
25
0
0
0
9
17
0
9
0
0
9
0
0
0
9
% R
% Ser:
34
34
17
25
34
17
25
25
9
17
9
25
34
17
17
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _