KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACE1
All Species:
29.39
Human Site:
Y296
Identified Species:
58.79
UniProt:
Q8WV93
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV93
NP_660358.2
481
54845
Y296
P
A
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093944
481
54837
Y296
P
A
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Dog
Lupus familis
XP_539073
457
52718
Y272
P
A
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3V384
480
54295
Y296
A
P
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Rat
Rattus norvegicus
Q32PX9
480
54484
Y296
T
P
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511224
853
93854
Y668
P
A
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Chicken
Gallus gallus
XP_419799
492
56007
Y305
P
A
A
G
K
L
Y
Y
L
T
S
E
A
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TYS0
503
57582
Y318
K
P
A
G
R
L
Y
Y
I
S
S
E
P
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
A406
E
S
H
G
H
V
G
A
D
L
A
S
L
C
S
Honey Bee
Apis mellifera
XP_624398
436
50701
F252
L
G
N
E
K
I
Y
F
I
K
G
K
D
A
I
Nematode Worm
Caenorhab. elegans
NP_491986
445
51394
F252
G
D
G
N
H
V
Y
F
S
S
E
D
S
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32317
509
58246
F290
P
V
S
S
V
Y
Y
F
P
S
D
T
S
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
86.2
N.A.
86.9
85.8
N.A.
48.7
73.7
N.A.
49.5
N.A.
20.3
46.3
39.7
N.A.
Protein Similarity:
100
N.A.
97.7
90.4
N.A.
91.6
90.8
N.A.
52.7
83.9
N.A.
67.1
N.A.
32.5
62.9
56.1
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
100
100
N.A.
53.3
N.A.
6.6
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
100
100
N.A.
73.3
N.A.
26.6
46.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
67
0
0
0
0
9
0
0
9
0
59
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
9
9
9
67
0
% D
% Glu:
9
0
0
9
0
0
0
0
0
0
9
67
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
75
0
0
9
0
0
0
9
0
0
0
0
% G
% His:
0
0
9
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
17
0
0
0
0
9
9
% I
% Lys:
9
0
0
0
67
0
0
0
0
9
0
9
0
0
9
% K
% Leu:
9
0
0
0
0
67
0
0
59
9
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
50
25
0
0
0
0
0
0
9
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
9
0
0
0
0
9
25
67
9
17
0
9
% S
% Thr:
9
0
0
0
0
0
0
0
0
59
0
9
0
0
9
% T
% Val:
0
9
0
0
9
17
0
0
0
0
0
0
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
92
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _