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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACE1
All Species:
37.27
Human Site:
T370
Identified Species:
74.55
UniProt:
Q8WV93
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV93
NP_660358.2
481
54845
T370
E
L
S
K
N
F
D
T
I
F
L
R
N
I
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093944
481
54837
T370
E
L
S
K
N
F
D
T
I
F
L
R
N
I
P
Dog
Lupus familis
XP_539073
457
52718
T346
E
L
S
K
N
F
D
T
V
F
L
R
N
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V384
480
54295
T370
E
L
S
K
N
F
D
T
V
I
I
R
N
I
P
Rat
Rattus norvegicus
Q32PX9
480
54484
T370
E
L
S
K
N
F
D
T
V
I
I
R
N
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511224
853
93854
T742
E
L
S
K
N
F
D
T
V
F
V
R
N
I
P
Chicken
Gallus gallus
XP_419799
492
56007
T379
E
I
S
K
H
F
D
T
V
F
V
R
D
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TYS0
503
57582
T392
E
I
A
R
C
F
D
T
V
I
I
R
N
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
K581
D
E
L
D
S
I
A
K
A
R
G
G
N
V
G
Honey Bee
Apis mellifera
XP_624398
436
50701
T325
E
L
S
Q
A
F
H
T
V
I
I
R
D
V
P
Nematode Worm
Caenorhab. elegans
NP_491986
445
51394
T324
V
Y
A
R
V
F
H
T
V
I
V
R
N
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32317
509
58246
A386
T
L
A
K
N
F
E
A
F
I
V
T
D
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
86.2
N.A.
86.9
85.8
N.A.
48.7
73.7
N.A.
49.5
N.A.
20.3
46.3
39.7
N.A.
Protein Similarity:
100
N.A.
97.7
90.4
N.A.
91.6
90.8
N.A.
52.7
83.9
N.A.
67.1
N.A.
32.5
62.9
56.1
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
80
80
N.A.
86.6
66.6
N.A.
46.6
N.A.
6.6
46.6
40
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
100
N.A.
86.6
N.A.
26.6
80
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
9
0
9
9
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
67
0
0
0
0
0
25
0
0
% D
% Glu:
75
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
92
0
0
9
42
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% G
% His:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
9
0
0
17
50
34
0
0
75
0
% I
% Lys:
0
0
0
67
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
67
9
0
0
0
0
0
0
0
25
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
59
0
0
0
0
0
0
0
75
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
92
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
9
0
84
0
0
0
% R
% Ser:
0
0
67
0
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
84
0
0
0
9
0
0
0
% T
% Val:
9
0
0
0
9
0
0
0
67
0
34
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _