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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACE1
All Species:
24.24
Human Site:
S428
Identified Species:
48.48
UniProt:
Q8WV93
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV93
NP_660358.2
481
54845
S428
H
D
S
E
L
E
Q
S
R
I
L
M
D
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093944
481
54837
S428
H
D
S
E
L
E
Q
S
R
I
L
M
D
D
L
Dog
Lupus familis
XP_539073
457
52718
S404
H
D
S
E
L
E
H
S
R
I
L
M
D
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3V384
480
54295
S428
Q
D
S
E
S
D
Q
S
R
I
L
M
D
D
L
Rat
Rattus norvegicus
Q32PX9
480
54484
S428
Q
D
S
E
S
D
Q
S
R
V
L
M
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511224
853
93854
S800
H
D
S
P
L
E
Q
S
R
I
L
M
D
D
L
Chicken
Gallus gallus
XP_419799
492
56007
S437
G
S
I
E
L
E
D
S
R
V
L
M
D
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TYS0
503
57582
D450
M
T
G
E
E
A
R
D
R
L
M
L
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
L639
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Honey Bee
Apis mellifera
XP_624398
436
50701
K383
N
N
E
Y
T
D
E
K
R
M
L
M
D
D
L
Nematode Worm
Caenorhab. elegans
NP_491986
445
51394
L382
H
N
T
S
H
D
A
L
S
D
S
K
R
M
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32317
509
58246
L444
Q
I
L
N
D
F
E
L
R
P
T
T
K
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
86.2
N.A.
86.9
85.8
N.A.
48.7
73.7
N.A.
49.5
N.A.
20.3
46.3
39.7
N.A.
Protein Similarity:
100
N.A.
97.7
90.4
N.A.
91.6
90.8
N.A.
52.7
83.9
N.A.
67.1
N.A.
32.5
62.9
56.1
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
80
73.3
N.A.
93.3
66.6
N.A.
26.6
N.A.
13.3
40
13.3
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
93.3
73.3
N.A.
60
N.A.
26.6
73.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
0
9
42
9
9
0
9
0
0
75
67
9
% D
% Glu:
0
0
9
59
9
42
17
0
0
0
0
0
0
17
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
42
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
9
42
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
9
9
0
0
% K
% Leu:
0
0
9
0
50
0
0
25
0
9
67
9
9
0
84
% L
% Met:
9
0
0
0
0
0
0
0
0
9
9
67
0
9
0
% M
% Asn:
9
17
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
9
0
9
0
9
9
% P
% Gln:
25
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
9
0
84
0
0
0
9
0
0
% R
% Ser:
0
9
50
9
17
0
0
59
9
0
9
0
0
0
0
% S
% Thr:
0
9
9
0
9
0
0
0
0
0
9
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _