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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6IP
All Species:
33.03
Human Site:
T542
Identified Species:
51.9
UniProt:
Q8WUM4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM4
NP_037506.2
868
96023
T542
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Chimpanzee
Pan troglodytes
XP_001169526
868
96035
T542
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534215
869
96105
T542
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU78
869
95992
T542
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Rat
Rattus norvegicus
Q9QZA2
873
96612
T547
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520983
801
88429
R485
N
E
V
V
N
V
L
R
S
L
L
S
N
L
D
Chicken
Gallus gallus
NP_001026164
882
97297
T546
P
S
A
N
P
A
K
T
L
Q
G
S
E
V
V
Frog
Xenopus laevis
Q9W6C5
867
96180
T541
P
S
A
N
P
A
K
T
M
Q
G
S
E
V
V
Zebra Danio
Brachydanio rerio
NP_998525
866
95753
T539
P
S
A
N
P
A
K
T
L
Q
G
S
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651582
836
92520
R513
I
E
A
D
K
V
V
R
Q
K
F
E
A
N
Q
Honey Bee
Apis mellifera
XP_396117
816
91664
A498
Y
R
E
I
I
N
N
A
V
A
A
D
K
V
V
Nematode Worm
Caenorhab. elegans
P34552
882
98246
T549
P
G
Q
T
A
H
A
T
G
E
T
D
T
V
R
Sea Urchin
Strong. purpuratus
XP_001204017
886
97596
A544
P
S
A
S
G
A
S
A
L
Q
G
S
P
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12033
661
75929
C345
P
I
E
V
M
E
Y
C
T
A
Y
N
E
R
Q
Red Bread Mold
Neurospora crassa
Q7SAN9
1012
112176
V588
D
D
G
G
P
S
V
V
E
Q
I
Q
K
V
E
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97
N.A.
94.2
94.1
N.A.
81.6
83.9
76.9
73.1
N.A.
42.2
43
39.2
46.3
Protein Similarity:
100
99.8
N.A.
97.9
N.A.
96.6
96.3
N.A.
85.7
90.6
88.8
85
N.A.
60.9
60.9
57.2
63.8
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
93.3
100
93.3
N.A.
6.6
13.3
20
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
20
26.6
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
29.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
7
60
7
14
0
14
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
0
0
0
0
0
0
14
0
0
7
% D
% Glu:
0
14
14
0
0
7
0
0
7
7
0
7
60
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
7
7
7
7
0
0
0
7
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
7
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
54
0
0
7
0
0
14
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
20
7
7
0
0
7
0
% L
% Met:
0
0
0
0
7
0
0
0
40
0
0
0
0
0
0
% M
% Asn:
7
0
0
54
7
7
7
0
0
0
0
7
7
7
0
% N
% Pro:
74
0
0
0
60
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
7
67
0
7
0
0
14
% Q
% Arg:
0
7
0
0
0
0
0
14
0
0
0
0
0
7
7
% R
% Ser:
0
60
0
7
0
7
7
0
7
0
0
67
0
0
0
% S
% Thr:
0
0
0
7
0
0
0
60
7
0
7
0
7
0
0
% T
% Val:
0
0
7
14
0
14
14
7
7
0
0
0
0
80
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _