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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6IP
All Species:
24.24
Human Site:
T286
Identified Species:
38.1
UniProt:
Q8WUM4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM4
NP_037506.2
868
96023
T286
H
A
A
E
L
I
K
T
V
A
S
R
Y
D
E
Chimpanzee
Pan troglodytes
XP_001169526
868
96035
T286
H
A
A
E
L
I
K
T
V
A
S
R
Y
D
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534215
869
96105
T286
H
A
A
E
L
I
K
T
V
A
S
R
Y
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU78
869
95992
N286
H
A
A
E
L
I
K
N
V
A
S
R
Y
D
E
Rat
Rattus norvegicus
Q9QZA2
873
96612
N291
H
A
A
E
L
I
K
N
V
A
S
R
Y
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520983
801
88429
K244
N
R
A
L
T
A
A
K
K
D
N
D
F
I
Y
Chicken
Gallus gallus
NP_001026164
882
97297
T290
H
A
A
D
L
V
K
T
V
A
S
R
Y
D
E
Frog
Xenopus laevis
Q9W6C5
867
96180
T285
H
A
S
D
L
V
K
T
V
S
S
R
Y
D
E
Zebra Danio
Brachydanio rerio
NP_998525
866
95753
T283
H
A
Q
E
L
V
K
T
A
A
S
R
Y
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651582
836
92520
A268
Y
Q
S
L
V
C
R
A
A
K
K
I
G
E
E
Honey Bee
Apis mellifera
XP_396117
816
91664
S257
A
M
T
E
F
Y
Q
S
L
V
C
K
N
N
K
Nematode Worm
Caenorhab. elegans
P34552
882
98246
R281
Q
I
G
E
Q
L
S
R
L
A
E
S
L
K
L
Sea Urchin
Strong. purpuratus
XP_001204017
886
97596
E288
H
A
S
D
L
L
S
E
V
E
R
K
G
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12033
661
75929
W104
T
S
Q
Y
S
L
Q
W
E
K
L
T
I
I
Y
Red Bread Mold
Neurospora crassa
Q7SAN9
1012
112176
G272
A
R
L
E
I
A
Q
G
L
A
K
E
A
N
K
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97
N.A.
94.2
94.1
N.A.
81.6
83.9
76.9
73.1
N.A.
42.2
43
39.2
46.3
Protein Similarity:
100
99.8
N.A.
97.9
N.A.
96.6
96.3
N.A.
85.7
90.6
88.8
85
N.A.
60.9
60.9
57.2
63.8
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
86.6
73.3
80
N.A.
6.6
6.6
13.3
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
26.6
100
100
86.6
N.A.
40
46.6
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
29.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
60
47
0
0
14
7
7
14
60
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
7
0
7
0
54
0
% D
% Glu:
0
0
0
60
0
0
0
7
7
7
7
7
0
7
60
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
0
0
0
0
14
7
0
% G
% His:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
34
0
0
0
0
0
7
7
14
0
% I
% Lys:
0
0
0
0
0
0
54
7
7
14
14
14
0
7
14
% K
% Leu:
0
0
7
14
60
20
0
0
20
0
7
0
7
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
14
0
0
7
0
7
14
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
14
0
7
0
20
0
0
0
0
0
0
0
7
% Q
% Arg:
0
14
0
0
0
0
7
7
0
0
7
54
0
0
0
% R
% Ser:
0
7
20
0
7
0
14
7
0
7
54
7
0
0
0
% S
% Thr:
7
0
7
0
7
0
0
40
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
7
20
0
0
54
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
7
0
0
0
0
0
0
54
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _