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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5D2 All Species: 21.21
Human Site: Y73 Identified Species: 35.9
UniProt: Q8WUJ1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ1 NP_653212.1 264 28690 Y73 V S S G R R H Y E P G S H Y S
Chimpanzee Pan troglodytes XP_511279 208 22411 G25 D S A A E S V G I T G R D A S
Rhesus Macaque Macaca mulatta XP_001093128 264 28902 Y73 V S S G R R H Y E P G S H Y S
Dog Lupus familis XP_546555 263 28295 Y72 V S P G R R H Y E P G A H Y S
Cat Felis silvestris
Mouse Mus musculus Q5SSH8 263 29144 Y73 V S S G R R H Y E P G A H Y S
Rat Rattus norvegicus Q6AY62 263 29046 Y73 V S S G R K H Y E P G A H Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516188 183 19692
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 E44 W L R Q R V S E V S A S S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 S101 R G I K H Y G S G C S Y N F F
Honey Bee Apis mellifera XP_001120049 206 23597 G24 K Y T N L E N G L Y I S I L G
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 Y136 V D G K K E Y Y G P G K S Y H
Sea Urchin Strong. purpuratus XP_795139 281 30858 R50 E L V G L F S R E N V A G T A
Poplar Tree Populus trichocarpa XP_002323190 250 27832 S40 P F K S F R N S L Q Q Q R L F
Maize Zea mays NP_001136676 237 26324 N45 L S V Y N G T N E E L P I L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.4 95.8 79.9 N.A. 80.6 80.3 N.A. 41.2 N.A. N.A. 44.9 N.A. 35.8 34.4 35.5 38.7
Protein Similarity: 100 74.6 97.7 85.2 N.A. 88.6 88.6 N.A. 50 N.A. N.A. 60.6 N.A. 49.1 52.6 48.7 54.8
P-Site Identity: 100 20 100 86.6 N.A. 93.3 86.6 N.A. 0 N.A. N.A. 13.3 N.A. 0 6.6 33.3 13.3
P-Site Similarity: 100 26.6 100 93.3 N.A. 100 100 N.A. 0 N.A. N.A. 13.3 N.A. 13.3 20 46.6 26.6
Percent
Protein Identity: 32.5 35.9 N.A. N.A. N.A. N.A.
Protein Similarity: 49.6 52.2 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 0 0 8 29 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 0 0 0 8 15 0 8 50 8 0 0 0 0 0 % E
% Phe: 0 8 0 0 8 8 0 0 0 0 0 0 0 8 15 % F
% Gly: 0 8 8 43 0 8 8 15 15 0 50 0 8 0 15 % G
% His: 0 0 0 0 8 0 36 0 0 0 0 0 36 0 8 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 8 0 15 0 0 % I
% Lys: 8 0 8 15 8 8 0 0 0 0 0 8 0 0 0 % K
% Leu: 8 15 0 0 15 0 0 0 15 0 8 0 0 22 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 15 8 0 8 0 0 8 0 0 % N
% Pro: 8 0 8 0 0 0 0 0 0 43 0 8 0 8 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 8 8 8 0 0 0 % Q
% Arg: 8 0 8 0 43 36 0 8 0 0 0 8 8 0 0 % R
% Ser: 0 50 29 8 0 8 15 15 0 8 8 29 15 0 43 % S
% Thr: 0 0 8 0 0 0 8 0 0 8 0 0 0 8 0 % T
% Val: 43 0 15 0 0 8 8 0 8 0 8 0 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 8 8 43 0 8 0 8 0 43 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _