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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5D2
All Species:
30.61
Human Site:
Y250
Identified Species:
51.79
UniProt:
Q8WUJ1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUJ1
NP_653212.1
264
28690
Y250
D
H
P
N
L
A
E
Y
T
G
C
P
P
L
A
Chimpanzee
Pan troglodytes
XP_511279
208
22411
Y194
D
H
P
N
L
A
E
Y
T
G
C
P
P
L
A
Rhesus Macaque
Macaca mulatta
XP_001093128
264
28902
Y250
D
H
P
N
L
A
E
Y
T
G
C
P
P
L
A
Dog
Lupus familis
XP_546555
263
28295
Y249
D
N
P
G
L
G
E
Y
A
G
C
P
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSH8
263
29144
Y249
D
N
P
N
L
E
E
Y
T
G
C
P
P
L
A
Rat
Rattus norvegicus
Q6AY62
263
29046
Y249
D
N
P
N
L
E
E
Y
T
G
C
P
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516188
183
19692
P170
P
R
A
G
G
G
E
P
V
P
P
Q
D
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CES0
267
29696
Y252
E
N
R
N
L
R
E
Y
T
D
C
P
P
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W376
287
32609
Y273
G
D
A
M
L
K
P
Y
D
N
C
E
P
Q
A
Honey Bee
Apis mellifera
XP_001120049
206
23597
C193
M
L
R
D
Y
P
Q
C
P
K
S
S
I
K
C
Nematode Worm
Caenorhab. elegans
Q9XXA7
326
36224
F312
D
H
P
D
L
E
L
F
P
D
C
S
P
T
S
Sea Urchin
Strong. purpuratus
XP_795139
281
30858
Y267
H
N
P
H
L
R
L
Y
D
N
C
P
L
R
S
Poplar Tree
Populus trichocarpa
XP_002323190
250
27832
I212
L
V
Q
R
P
L
E
I
A
L
T
G
K
M
S
Maize
Zea mays
NP_001136676
237
26324
Y224
D
K
A
G
L
V
V
Y
E
G
C
D
Y
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
95.8
79.9
N.A.
80.6
80.3
N.A.
41.2
N.A.
N.A.
44.9
N.A.
35.8
34.4
35.5
38.7
Protein Similarity:
100
74.6
97.7
85.2
N.A.
88.6
88.6
N.A.
50
N.A.
N.A.
60.6
N.A.
49.1
52.6
48.7
54.8
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
6.6
N.A.
N.A.
60
N.A.
33.3
0
40
33.3
P-Site Similarity:
100
100
100
80
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
73.3
N.A.
33.3
13.3
60
53.3
Percent
Protein Identity:
32.5
35.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
52.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
0
22
0
0
15
0
0
0
0
0
58
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
79
0
0
0
8
% C
% Asp:
58
8
0
15
0
0
0
0
15
15
0
8
8
0
0
% D
% Glu:
8
0
0
0
0
22
65
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
22
8
15
0
0
0
50
0
8
0
0
0
% G
% His:
8
29
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
8
0
0
8
8
0
% K
% Leu:
8
8
0
0
79
8
15
0
0
8
0
0
8
50
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
36
0
43
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
8
0
58
0
8
8
8
8
15
8
8
58
65
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
0
8
15
8
0
15
0
0
0
0
0
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
15
0
0
29
% S
% Thr:
0
0
0
0
0
0
0
0
43
0
8
0
0
8
0
% T
% Val:
0
8
0
0
0
8
8
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
72
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _