KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5D2
All Species:
4.55
Human Site:
T171
Identified Species:
7.69
UniProt:
Q8WUJ1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUJ1
NP_653212.1
264
28690
T171
L
Q
L
Q
E
K
Q
T
F
P
P
C
N
A
E
Chimpanzee
Pan troglodytes
XP_511279
208
22411
W123
F
P
P
C
N
A
E
W
S
S
A
R
G
S
R
Rhesus Macaque
Macaca mulatta
XP_001093128
264
28902
T171
L
E
L
Q
E
K
Q
T
F
P
P
C
N
A
E
Dog
Lupus familis
XP_546555
263
28295
K170
R
A
L
Q
E
K
Q
K
F
P
P
C
N
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSH8
263
29144
K171
Q
E
Q
R
E
K
Q
K
F
P
P
C
N
S
E
Rat
Rattus norvegicus
Q6AY62
263
29046
R171
Q
E
Q
R
E
K
Q
R
F
P
P
C
N
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516188
183
19692
L99
D
G
E
P
T
Q
A
L
V
L
A
E
A
A
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CES0
267
29696
D142
W
L
S
F
Y
Q
R
D
Y
T
P
V
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W376
287
32609
R199
Q
V
E
E
L
R
A
R
Y
P
G
C
N
I
E
Honey Bee
Apis mellifera
XP_001120049
206
23597
Q122
T
K
E
L
H
K
K
Q
M
F
P
P
C
N
I
Nematode Worm
Caenorhab. elegans
Q9XXA7
326
36224
V234
A
Q
A
V
E
I
E
V
F
P
P
C
N
S
E
Sea Urchin
Strong. purpuratus
XP_795139
281
30858
I148
G
L
T
P
Q
D
M
I
G
L
E
D
W
V
K
Poplar Tree
Populus trichocarpa
XP_002323190
250
27832
F138
F
Y
F
R
S
Y
T
F
V
G
K
L
V
G
R
Maize
Zea mays
NP_001136676
237
26324
L143
E
G
N
P
T
K
Y
L
K
G
V
E
V
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
95.8
79.9
N.A.
80.6
80.3
N.A.
41.2
N.A.
N.A.
44.9
N.A.
35.8
34.4
35.5
38.7
Protein Similarity:
100
74.6
97.7
85.2
N.A.
88.6
88.6
N.A.
50
N.A.
N.A.
60.6
N.A.
49.1
52.6
48.7
54.8
P-Site Identity:
100
0
93.3
80
N.A.
60
66.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
26.6
13.3
53.3
0
P-Site Similarity:
100
13.3
100
80
N.A.
80
80
N.A.
13.3
N.A.
N.A.
26.6
N.A.
46.6
26.6
66.6
13.3
Percent
Protein Identity:
32.5
35.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
52.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
15
0
0
0
15
0
8
36
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
50
8
0
0
% C
% Asp:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% D
% Glu:
8
22
22
8
43
0
15
0
0
0
8
15
0
0
50
% E
% Phe:
15
0
8
8
0
0
0
8
43
8
0
0
0
0
0
% F
% Gly:
8
15
0
0
0
0
0
0
8
15
8
0
15
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
15
% I
% Lys:
0
8
0
0
0
50
8
15
8
0
8
0
0
15
8
% K
% Leu:
15
15
22
8
8
0
0
15
0
15
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
50
8
0
% N
% Pro:
0
8
8
22
0
0
0
0
0
50
58
8
0
0
0
% P
% Gln:
22
15
15
22
8
15
36
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
22
0
8
8
15
0
0
0
8
0
0
15
% R
% Ser:
0
0
8
0
8
0
0
0
8
8
0
0
0
22
0
% S
% Thr:
8
0
8
0
15
0
8
15
0
8
0
0
0
0
0
% T
% Val:
0
8
0
8
0
0
0
8
15
0
8
8
15
8
0
% V
% Trp:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
8
8
8
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _