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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5D2
All Species:
19.39
Human Site:
S193
Identified Species:
32.82
UniProt:
Q8WUJ1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUJ1
NP_653212.1
264
28690
S193
R
L
W
C
S
Q
K
S
G
G
V
S
R
D
W
Chimpanzee
Pan troglodytes
XP_511279
208
22411
I145
G
G
V
S
R
D
W
I
G
V
P
R
K
L
Y
Rhesus Macaque
Macaca mulatta
XP_001093128
264
28902
S193
R
L
W
C
S
Q
K
S
G
G
V
S
R
D
W
Dog
Lupus familis
XP_546555
263
28295
S192
R
L
W
C
S
T
E
S
G
G
V
S
R
D
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSH8
263
29144
S193
R
L
W
C
S
Q
K
S
G
G
V
H
R
D
W
Rat
Rattus norvegicus
Q6AY62
263
29046
S193
R
L
W
C
S
Q
K
S
G
G
V
H
R
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516188
183
19692
R121
A
R
D
D
E
L
K
R
Q
F
P
P
C
N
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CES0
267
29696
L164
T
G
Q
P
T
D
A
L
L
H
V
E
A
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W376
287
32609
S221
R
V
W
C
T
T
T
S
G
D
G
K
E
R
S
Honey Bee
Apis mellifera
XP_001120049
206
23597
K144
T
V
V
W
C
T
K
K
S
G
G
I
E
R
N
Nematode Worm
Caenorhab. elegans
Q9XXA7
326
36224
G256
V
W
C
S
T
K
S
G
G
V
E
R
Q
W
A
Sea Urchin
Strong. purpuratus
XP_795139
281
30858
H170
Y
V
G
K
L
N
G
H
F
Y
D
E
R
G
E
Poplar Tree
Populus trichocarpa
XP_002323190
250
27832
V160
P
T
K
S
L
K
G
V
E
A
K
A
A
R
G
Maize
Zea mays
NP_001136676
237
26324
A165
E
K
Q
K
S
D
E
A
K
I
P
G
C
N
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
95.8
79.9
N.A.
80.6
80.3
N.A.
41.2
N.A.
N.A.
44.9
N.A.
35.8
34.4
35.5
38.7
Protein Similarity:
100
74.6
97.7
85.2
N.A.
88.6
88.6
N.A.
50
N.A.
N.A.
60.6
N.A.
49.1
52.6
48.7
54.8
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
33.3
13.3
6.6
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
13.3
N.A.
46.6
20
26.6
13.3
Percent
Protein Identity:
32.5
35.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
52.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
0
8
0
8
15
0
8
% A
% Cys:
0
0
8
43
8
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
0
0
8
8
0
22
0
0
0
8
8
0
0
36
0
% D
% Glu:
8
0
0
0
8
0
15
0
8
0
8
15
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% F
% Gly:
8
15
8
0
0
0
15
8
58
43
15
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
15
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% I
% Lys:
0
8
8
15
0
15
43
8
8
0
8
8
8
0
0
% K
% Leu:
0
36
0
0
15
8
0
8
8
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
15
8
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
22
8
0
0
0
% P
% Gln:
0
0
15
0
0
29
0
0
8
0
0
0
8
0
0
% Q
% Arg:
43
8
0
0
8
0
0
8
0
0
0
15
43
22
0
% R
% Ser:
0
0
0
22
43
0
8
43
8
0
0
22
0
0
22
% S
% Thr:
15
8
0
0
22
22
8
0
0
0
0
0
0
0
0
% T
% Val:
8
22
15
0
0
0
0
8
0
15
43
0
0
0
0
% V
% Trp:
0
8
43
8
0
0
8
0
0
0
0
0
0
8
36
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _