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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM172A
All Species:
6.67
Human Site:
T397
Identified Species:
14.67
UniProt:
Q8WUF8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUF8
NP_114431.2
416
47972
T397
T
E
A
S
E
A
K
T
S
S
L
K
P
A
V
Chimpanzee
Pan troglodytes
XP_001137302
370
42833
S352
E
A
S
E
A
K
T
S
S
L
K
P
A
V
T
Rhesus Macaque
Macaca mulatta
XP_001090575
416
47980
I397
T
E
A
S
E
A
K
I
S
S
L
K
P
A
V
Dog
Lupus familis
XP_851856
474
53890
G421
M
I
I
E
I
D
G
G
R
R
V
K
D
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TNH5
417
48054
S398
A
E
A
S
E
A
K
S
S
S
Q
K
P
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509434
355
41030
L337
W
V
S
S
S
E
P
L
D
A
S
V
E
S
M
Chicken
Gallus gallus
Q5ZK44
416
48335
N397
S
E
A
M
E
A
K
N
S
S
V
K
P
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T297
415
48190
E394
S
N
A
L
K
D
H
E
D
D
S
S
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RN0
325
36543
I307
E
W
T
S
Y
S
A
I
D
S
V
F
K
F
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XW78
313
35293
S295
A
K
K
L
V
V
K
S
E
N
S
K
E
S
D
Sea Urchin
Strong. purpuratus
XP_790439
454
51379
E420
D
E
G
S
Q
D
K
E
D
S
Q
E
E
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
99.5
74.8
N.A.
93
N.A.
N.A.
77.6
87.5
N.A.
73.8
N.A.
32.2
N.A.
26.9
27
Protein Similarity:
100
88.9
99.7
78.9
N.A.
96.6
N.A.
N.A.
82.6
94.2
N.A.
85
N.A.
46.8
N.A.
40.8
46.2
P-Site Identity:
100
6.6
93.3
6.6
N.A.
73.3
N.A.
N.A.
6.6
66.6
N.A.
6.6
N.A.
13.3
N.A.
13.3
26.6
P-Site Similarity:
100
20
93.3
13.3
N.A.
86.6
N.A.
N.A.
33.3
80
N.A.
26.6
N.A.
33.3
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
46
0
10
37
10
0
0
10
0
0
10
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
28
0
0
37
10
0
0
10
0
10
% D
% Glu:
19
46
0
19
37
10
0
19
10
0
0
10
28
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
0
0
19
0
0
0
0
0
10
10
% I
% Lys:
0
10
10
0
10
10
55
0
0
0
10
55
10
0
0
% K
% Leu:
0
0
0
19
0
0
0
10
0
10
19
0
0
0
10
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
10
37
0
28
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% R
% Ser:
19
0
19
55
10
10
0
28
46
55
28
10
10
28
0
% S
% Thr:
19
0
10
0
0
0
10
10
0
0
0
0
0
0
10
% T
% Val:
0
10
0
0
10
10
0
0
0
0
28
10
0
10
19
% V
% Trp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _