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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM172A
All Species:
13.94
Human Site:
S219
Identified Species:
30.67
UniProt:
Q8WUF8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUF8
NP_114431.2
416
47972
S219
H
V
Q
S
S
S
D
S
S
D
E
P
A
E
K
Chimpanzee
Pan troglodytes
XP_001137302
370
42833
D185
A
E
K
R
E
R
K
D
K
V
S
K
E
T
K
Rhesus Macaque
Macaca mulatta
XP_001090575
416
47980
S219
H
V
Q
S
S
S
D
S
S
D
E
P
A
E
K
Dog
Lupus familis
XP_851856
474
53890
S243
H
V
Q
S
S
S
D
S
S
D
E
P
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TNH5
417
48054
G220
K
Q
S
S
S
S
D
G
T
D
E
P
A
G
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509434
355
41030
R170
T
Q
I
P
Y
I
K
R
A
M
E
E
G
Y
G
Chicken
Gallus gallus
Q5ZK44
416
48335
S219
Q
V
Q
L
S
S
D
S
S
D
E
P
A
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T297
415
48190
P216
D
P
A
K
K
A
S
P
D
A
S
D
E
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RN0
325
36543
G140
G
S
G
Y
V
K
A
G
Q
W
A
R
S
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XW78
313
35293
G128
I
E
R
A
I
E
N
G
W
G
V
V
V
M
N
Sea Urchin
Strong. purpuratus
XP_790439
454
51379
S239
L
T
I
R
K
S
S
S
P
Y
E
H
G
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
99.5
74.8
N.A.
93
N.A.
N.A.
77.6
87.5
N.A.
73.8
N.A.
32.2
N.A.
26.9
27
Protein Similarity:
100
88.9
99.7
78.9
N.A.
96.6
N.A.
N.A.
82.6
94.2
N.A.
85
N.A.
46.8
N.A.
40.8
46.2
P-Site Identity:
100
6.6
100
100
N.A.
60
N.A.
N.A.
6.6
86.6
N.A.
0
N.A.
0
N.A.
0
20
P-Site Similarity:
100
13.3
100
100
N.A.
66.6
N.A.
N.A.
13.3
86.6
N.A.
6.6
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
10
10
0
10
10
10
0
46
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
46
10
10
46
0
10
0
0
0
% D
% Glu:
0
19
0
0
10
10
0
0
0
0
64
10
19
37
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
28
0
10
0
0
19
10
10
% G
% His:
28
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
19
0
10
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
10
10
19
10
19
0
10
0
0
10
0
0
55
% K
% Leu:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
10
0
10
0
0
0
10
10
0
0
46
0
10
0
% P
% Gln:
10
19
37
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
19
0
10
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
10
10
37
46
55
19
46
37
0
19
0
10
0
0
% S
% Thr:
10
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
37
0
0
10
0
0
0
0
10
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
10
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _