KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
21.82
Human Site:
S446
Identified Species:
34.29
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S446
Q
N
R
S
R
S
R
S
R
E
R
D
G
H
Y
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S561
Q
N
R
S
R
S
R
S
R
E
R
D
G
H
Y
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S446
Q
N
R
S
R
S
R
S
R
E
R
D
G
H
Y
Dog
Lupus familis
XP_541147
492
57155
S446
Q
N
R
S
R
S
R
S
R
E
R
D
G
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S446
Q
N
R
S
R
S
R
S
R
E
R
D
G
H
Y
Rat
Rattus norvegicus
NP_001101927
357
40656
H312
L
I
D
D
R
R
I
H
V
D
F
S
Q
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
S442
Q
S
R
S
R
S
R
S
R
D
T
D
N
R
H
Chicken
Gallus gallus
XP_419663
478
55881
R432
K
K
D
R
H
R
S
R
S
R
S
Q
E
R
S
Frog
Xenopus laevis
Q6GLX7
477
54856
W424
D
E
E
N
D
K
G
W
L
S
H
V
L
Q
F
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
K408
R
D
E
S
R
R
E
K
D
R
S
R
Q
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
R481
R
S
R
D
Q
K
E
R
R
R
S
R
P
R
E
Honey Bee
Apis mellifera
XP_001121334
512
60307
D439
R
S
R
S
R
S
R
D
K
S
K
R
E
N
Y
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
R382
R
R
E
P
A
R
R
R
R
S
S
D
N
H
R
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
R486
R
G
D
E
D
R
K
R
R
K
D
E
R
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
D443
D
N
R
R
G
P
R
D
A
D
R
R
R
D
D
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
60
0
0
13.3
N.A.
13.3
40
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
80
6.6
13.3
26.6
N.A.
33.3
73.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
20
14
14
0
0
14
7
20
7
47
0
7
7
% D
% Glu:
0
7
20
7
0
0
14
0
0
34
0
7
14
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
7
0
0
7
0
7
0
0
0
0
0
34
0
0
% G
% His:
0
0
0
0
7
0
0
7
0
0
7
0
0
40
7
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
0
0
0
14
7
7
7
7
7
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
7
0
0
0
0
0
0
0
0
14
7
0
% N
% Pro:
0
0
0
7
0
7
0
0
0
0
0
0
7
0
0
% P
% Gln:
40
0
0
0
7
0
0
0
0
0
0
7
14
7
0
% Q
% Arg:
34
7
60
14
60
34
60
27
60
20
40
27
14
34
7
% R
% Ser:
0
20
0
54
0
47
7
40
7
20
27
7
0
7
14
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _