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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMAP2 All Species: 20.91
Human Site: S221 Identified Species: 35.38
UniProt: Q8WU79 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU79 NP_073570.1 429 46786 S221 L A S V P S P S S S G S R K V
Chimpanzee Pan troglodytes XP_513355 607 63762 S399 L A S V P S P S S S G S R K V
Rhesus Macaque Macaca mulatta XP_001083189 660 69891 S452 L A S V P S P S S S G S R K V
Dog Lupus familis XP_539575 405 44009 S197 L A S V P S P S S S V S R K V
Cat Felis silvestris
Mouse Mus musculus Q7TN29 428 46559 P220 L L A S V P S P S S V S R K A
Rat Rattus norvegicus NP_001094139 428 46475 P220 L L A S V P S P S S V S R K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507351 431 46646 S221 F A S A P S T S L P D S R K V
Chicken Gallus gallus Q5F413 428 46296 S220 F A S V G L N S D S R K V S G
Frog Xenopus laevis NP_001086060 421 45767 S205 P N G K P S T S L E K E L D L
Zebra Danio Brachydanio rerio NP_001038260 418 45253 A210 L F S S L P A A V S N S N S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610424 517 55013 G274 G Q P D K P I G S N G D A A N
Honey Bee Apis mellifera XP_623142 486 53406 P234 S S F L S A P P A S V A S T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL69 483 52574 T242 M L S M D D S T T N T S E A T
Baker's Yeast Sacchar. cerevisiae P40529 298 32620 E91 L R A N S Y Y E A T L A D E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.8 62.8 89.9 N.A. 95.5 95.5 N.A. 82.5 79.4 67.8 57.8 N.A. 32.6 33.7 N.A. N.A.
Protein Similarity: 100 69.1 63.4 92.7 N.A. 96.5 96.2 N.A. 90.2 88.5 78.7 69 N.A. 45.4 49.1 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 40 40 N.A. 60 33.3 20 26.6 N.A. 13.3 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 46.6 46.6 N.A. 60 33.3 26.6 33.3 N.A. 20 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.1 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 44.9 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 22 8 0 8 8 8 15 0 0 15 8 15 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 0 8 0 8 8 8 8 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 8 0 8 8 8 0 % E
% Phe: 15 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 8 0 0 8 0 0 29 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 0 8 8 0 50 0 % K
% Leu: 58 22 0 8 8 8 0 0 15 0 8 0 8 0 15 % L
% Met: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 8 0 0 15 8 0 8 0 8 % N
% Pro: 8 0 8 0 43 29 36 22 0 8 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 8 0 50 0 0 % R
% Ser: 8 8 58 22 15 43 22 50 50 65 0 65 8 15 0 % S
% Thr: 0 0 0 0 0 0 15 8 8 8 8 0 0 8 15 % T
% Val: 0 0 0 36 15 0 0 0 8 0 29 0 8 0 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _