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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSG2 All Species: 10.91
Human Site: S185 Identified Species: 18.46
UniProt: Q8TF76 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF76 NP_114171.2 798 88460 S185 G S P T P R D S V I S I G T S
Chimpanzee Pan troglodytes XP_001159222 798 88213 S185 G S P T P R D S V I S I G T S
Rhesus Macaque Macaca mulatta XP_001090778 800 88544 R188 G S P T P R D R A I S I G T S
Dog Lupus familis XP_854539 781 85828 S171 G P P A P G D S V L C T G P S
Cat Felis silvestris
Mouse Mus musculus Q9Z0R0 754 84163 S167 P D P L Y A D S A V P G S F H
Rat Rattus norvegicus XP_001080273 751 84077 V166 S L N A D S T V P G S L H F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425408 823 90214 A180 H D A S L G S A A N S P G T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686125 570 63516
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83103 566 65304
Honey Bee Apis mellifera XP_624666 678 78345 K100 K S E I N N H K S S L L E I C
Nematode Worm Caenorhab. elegans NP_492043 949 108321 S316 F D V S L N D S C E N I T K K
Sea Urchin Strong. purpuratus XP_784842 796 89784 S182 E Q K K T V T S S S S G D S V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149827 602 67250 G24 R A R P P R V G V V Y G R R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172416 599 67912 I21 S E E E D G D I P K I E A V F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 92.2 73.1 N.A. 61.9 62.6 N.A. N.A. 42.5 N.A. 36.2 N.A. 26.3 21.2 23.1 30
Protein Similarity: 100 99.1 95 80.6 N.A. 73 72.8 N.A. N.A. 57.7 N.A. 47.7 N.A. 42.9 37.8 40.1 47.1
P-Site Identity: 100 100 86.6 53.3 N.A. 20 6.6 N.A. N.A. 20 N.A. 0 N.A. 0 6.6 20 13.3
P-Site Similarity: 100 100 86.6 60 N.A. 26.6 13.3 N.A. N.A. 33.3 N.A. 0 N.A. 0 13.3 33.3 20
Percent
Protein Identity: N.A. 26 N.A. 26.1 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 15 0 8 0 8 22 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 8 % C
% Asp: 0 22 0 0 15 0 50 0 0 0 0 0 8 0 0 % D
% Glu: 8 8 15 8 0 0 0 0 0 8 0 8 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 15 8 % F
% Gly: 29 0 0 0 0 22 0 8 0 8 0 22 36 0 0 % G
% His: 8 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % H
% Ile: 0 0 0 8 0 0 0 8 0 22 8 29 0 8 0 % I
% Lys: 8 0 8 8 0 0 0 8 0 8 0 0 0 8 8 % K
% Leu: 0 8 0 8 15 0 0 0 0 8 8 15 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 15 0 0 0 8 8 0 0 0 0 % N
% Pro: 8 8 36 8 36 0 0 0 15 0 8 8 0 8 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 0 29 0 8 0 0 0 0 8 8 8 % R
% Ser: 15 29 0 15 0 8 8 43 15 15 43 0 8 8 29 % S
% Thr: 0 0 0 22 8 0 15 0 0 0 0 8 8 29 0 % T
% Val: 0 0 8 0 0 8 8 8 29 15 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _