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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMCR8
All Species:
13.94
Human Site:
S579
Identified Species:
38.33
UniProt:
Q8TEV9
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEV9
NP_658988.2
937
105022
S579
G
S
I
E
N
T
P
S
Q
I
D
S
S
C
C
Chimpanzee
Pan troglodytes
XP_001157693
937
105087
S579
G
S
I
E
N
T
P
S
Q
I
D
S
S
C
C
Rhesus Macaque
Macaca mulatta
XP_001095753
936
104926
S579
G
S
M
E
N
T
P
S
Q
I
D
S
C
C
I
Dog
Lupus familis
XP_851653
935
104212
S578
G
S
L
E
N
T
S
S
Q
A
D
S
S
C
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMB5
935
104939
Q578
N
L
E
N
I
P
S
Q
I
D
S
S
C
C
I
Rat
Rattus norvegicus
XP_573105
935
104980
Q578
N
L
E
N
I
P
S
Q
I
D
S
S
C
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509598
795
88016
S449
G
G
D
E
A
T
E
S
S
V
Y
G
H
R
E
Chicken
Gallus gallus
XP_414823
785
87340
D439
K
M
E
Q
D
M
D
D
P
Q
E
P
A
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PUR7
985
110585
G602
A
L
E
G
L
K
Q
G
R
V
P
T
R
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
91.3
N.A.
89.9
90
N.A.
63.7
59.5
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.2
94.6
N.A.
93.3
94.1
N.A.
69.9
67.6
N.A.
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
80
N.A.
13.3
13.3
N.A.
26.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
13.3
13.3
N.A.
33.3
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
12
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
34
67
34
% C
% Asp:
0
0
12
0
12
0
12
12
0
23
45
0
0
0
0
% D
% Glu:
0
0
45
56
0
0
12
0
0
0
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
12
0
12
0
0
0
12
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
23
0
23
0
0
0
23
34
0
0
0
0
34
% I
% Lys:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
34
12
0
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
12
12
0
0
12
0
0
0
0
0
0
0
12
0
% M
% Asn:
23
0
0
23
45
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
23
34
0
12
0
12
12
0
0
0
% P
% Gln:
0
0
0
12
0
0
12
23
45
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
12
23
0
% R
% Ser:
0
45
0
0
0
0
34
56
12
0
23
67
34
0
0
% S
% Thr:
0
0
0
0
0
56
0
0
0
0
0
12
0
0
23
% T
% Val:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _