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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
27.27
Human Site:
Y326
Identified Species:
50
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
Y326
E
R
S
I
E
E
V
Y
Y
L
W
C
L
A
G
Chimpanzee
Pan troglodytes
XP_526648
893
100716
Y326
E
R
S
I
E
E
V
Y
Y
L
W
C
L
A
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
Y326
E
R
S
I
E
E
V
Y
Y
L
W
C
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
G234
I
V
L
A
E
E
H
G
C
L
D
I
I
K
E
Rat
Rattus norvegicus
NP_001127985
860
96794
I322
D
Y
L
A
E
R
S
I
E
E
V
Y
Y
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
S326
S
D
Y
L
A
E
R
S
I
E
E
V
Y
Y
L
Chicken
Gallus gallus
Q5F361
893
100434
Y326
E
R
S
I
E
E
V
Y
Y
L
W
C
L
A
G
Frog
Xenopus laevis
NP_001087131
893
100210
Y326
E
R
S
I
E
E
V
Y
H
L
W
C
L
A
G
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
Y326
E
R
A
I
D
E
V
Y
H
L
W
C
L
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
C291
H
L
P
L
L
L
R
C
P
L
S
Q
I
Y
H
Honey Bee
Apis mellifera
XP_393033
792
90269
F264
K
L
P
I
F
E
E
F
L
K
M
D
E
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
Y344
Q
R
P
M
K
E
V
Y
Y
L
W
T
L
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
20
6.6
N.A.
6.6
100
93.3
80
N.A.
6.6
13.3
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
26.6
13.3
N.A.
13.3
100
100
100
N.A.
20
26.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
8
0
0
0
0
0
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
47
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
47
0
0
0
54
77
8
0
8
16
8
0
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
54
% G
% His:
8
0
0
0
0
0
8
0
16
0
0
0
0
0
8
% H
% Ile:
8
0
0
54
0
0
0
8
8
0
0
8
16
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
16
16
16
8
8
0
0
8
70
0
0
54
16
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
24
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
54
0
0
0
8
16
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
39
0
0
0
8
8
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
8
0
0
0
0
54
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
8
% W
% Tyr:
0
8
8
0
0
0
0
54
39
0
0
8
16
16
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _