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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
17.88
Human Site:
T300
Identified Species:
32.78
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
T300
S
L
R
C
A
D
L
T
L
P
E
D
I
S
Q
Chimpanzee
Pan troglodytes
XP_526648
893
100716
T300
S
L
R
C
A
D
L
T
L
P
E
D
I
S
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
T300
S
L
R
C
A
D
L
T
L
P
E
D
I
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
D208
R
K
L
F
Q
S
L
D
V
S
E
R
V
K
F
Rat
Rattus norvegicus
NP_001127985
860
96794
C296
L
F
S
S
S
L
R
C
A
D
L
T
L
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
T300
S
L
R
C
A
D
L
T
L
P
E
D
I
S
Q
Chicken
Gallus gallus
Q5F361
893
100434
T300
S
P
R
C
A
D
L
T
L
P
E
D
I
S
Q
Frog
Xenopus laevis
NP_001087131
893
100210
I300
A
L
R
C
A
D
L
I
L
P
D
D
I
S
L
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
Q300
S
P
R
C
A
Y
L
Q
L
P
D
D
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
E265
L
E
H
P
I
F
E
E
V
L
L
D
L
K
K
Honey Bee
Apis mellifera
XP_393033
792
90269
V238
P
D
K
V
K
E
F
V
D
S
C
L
Q
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
E318
G
L
R
C
K
D
L
E
L
D
T
D
Q
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
0
N.A.
100
93.3
73.3
66.6
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
26.6
20
N.A.
100
93.3
86.6
80
N.A.
26.6
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
54
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
62
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
54
0
8
8
16
16
70
0
8
8
% D
% Glu:
0
8
0
0
0
8
8
16
0
0
47
0
0
0
16
% E
% Phe:
0
8
0
8
0
8
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
54
8
0
% I
% Lys:
0
8
8
0
16
0
0
0
0
0
0
0
0
16
8
% K
% Leu:
16
47
8
0
0
8
70
0
62
8
16
8
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
16
0
8
0
0
0
0
0
54
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
16
0
39
% Q
% Arg:
8
0
62
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
47
0
8
8
8
8
0
0
0
16
0
0
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
39
0
0
8
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
8
16
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _