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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
10.91
Human Site:
T284
Identified Species:
20
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
T284
S
P
L
Y
T
P
F
T
K
P
A
S
L
F
S
Chimpanzee
Pan troglodytes
XP_526648
893
100716
T284
S
P
L
Y
T
P
F
T
K
P
A
S
L
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
T284
S
P
L
Y
T
P
F
T
K
P
A
S
L
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
I192
S
D
V
W
S
L
G
I
I
L
F
E
L
C
V
Rat
Rattus norvegicus
NP_001127985
860
96794
Y280
F
S
E
V
S
P
L
Y
T
P
F
I
K
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
H284
S
P
L
Y
P
S
F
H
K
P
A
G
L
F
S
Chicken
Gallus gallus
Q5F361
893
100434
H284
S
L
T
Y
P
P
F
H
K
P
A
G
L
F
S
Frog
Xenopus laevis
NP_001087131
893
100210
R284
S
P
L
Y
I
P
F
R
K
P
V
G
L
F
S
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
Q284
S
S
E
Y
T
P
Y
Q
S
P
V
H
L
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
K249
S
C
L
S
V
L
P
K
R
R
P
L
P
G
E
Honey Bee
Apis mellifera
XP_393033
792
90269
N222
E
R
L
A
R
E
T
N
C
Y
N
T
Y
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
S302
P
S
E
L
L
P
P
S
S
L
T
M
F
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
73.3
66.6
73.3
53.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
33.3
26.6
N.A.
73.3
66.6
73.3
60
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
39
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
24
0
0
8
0
0
0
0
0
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
47
0
0
0
16
0
8
54
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
24
0
8
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
47
0
0
0
8
8
0
% K
% Leu:
0
8
54
8
8
16
8
0
0
16
0
8
62
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
8
39
0
0
16
62
16
0
0
62
8
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
8
8
8
0
0
0
8
0
% R
% Ser:
70
24
0
8
16
8
0
8
16
0
0
24
0
0
54
% S
% Thr:
0
0
8
0
31
0
8
24
8
0
8
8
0
0
0
% T
% Val:
0
0
8
8
8
0
0
0
0
0
16
0
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
54
0
0
8
8
0
8
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _