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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
28.48
Human Site:
S384
Identified Species:
52.22
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
S384
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Chimpanzee
Pan troglodytes
XP_526648
893
100716
S384
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
S384
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
P286
L
Y
T
P
F
I
K
P
A
S
L
F
S
S
S
Rat
Rattus norvegicus
NP_001127985
860
96794
S375
P
L
L
E
D
D
Q
S
S
L
P
H
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
S389
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Chicken
Gallus gallus
Q5F361
893
100434
S384
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Frog
Xenopus laevis
NP_001087131
893
100210
S384
D
D
T
T
V
T
L
S
L
C
Q
L
R
N
R
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
S384
D
D
T
T
V
T
L
S
L
F
Q
L
R
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
Q343
S
V
C
P
G
R
S
Q
A
Q
L
M
D
D
R
Honey Bee
Apis mellifera
XP_393033
792
90269
T316
Q
M
F
G
R
R
D
T
A
G
L
L
D
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
D396
D
T
S
S
L
N
D
D
T
V
V
I
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
A30
P
V
N
L
V
Q
N
A
K
S
T
N
D
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
13.3
N.A.
100
100
100
93.3
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
100
100
100
93.3
N.A.
20
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
24
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
47
0
0
0
0
0
% C
% Asp:
62
54
0
0
8
8
16
8
0
0
0
0
24
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
8
8
8
0
54
0
54
8
24
62
8
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
8
8
0
0
0
0
8
0
62
0
% N
% Pro:
16
0
0
16
0
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
8
8
0
8
54
0
0
0
8
% Q
% Arg:
0
0
0
0
8
16
0
0
0
0
0
0
54
0
70
% R
% Ser:
8
0
8
8
0
0
8
62
8
16
0
0
16
16
16
% S
% Thr:
0
8
62
54
0
54
0
8
8
0
8
0
0
0
0
% T
% Val:
0
16
0
0
62
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _